Results 21 to 30 of about 911,597 (272)
Automated discovery of novel drug formulations using predictive iterated high throughput experimentation. [PDF]
PLoS ONE, 2010 BACKGROUND: We consider the problem of optimizing a liposomal drug formulation: a complex chemical system with many components (e.g., elements of a lipid library) that interact nonlinearly and synergistically in ways that cannot be predicted from first ...
Filippo Caschera +7 more
doaj +1 more source
O Domínio da Economia Subjetiva:
Mises, 2014 O autor explica que a discussão sobre a metodologia da economia subjetiva precisa considerar um fato e uma hipótese. O fato é que, em qualquer ciência do comportamento humano, o observador está ele próprio em meio ao observado e a hipótese é que os seres
James M. Buchanan
doaj +1 more source
Estudos EconômicosO objetivo do presente artigo é contribuir com o estudo a respeito da trajetória intelectual de James M. Buchanan. O artigo argumenta que a tradição italiana de finanças públicas foi um importante canal de transmissão das ideias da economia política ...
Gustavo Nunes Mourão, Eduardo Angeli
doaj +1 more source
BMC Cancer, 2022 Background Ovarian cancer is initially responsive to frontline chemotherapy. Unfortunately, it often recurs and becomes resistant to available therapies and the survival rate for advanced and recurrent ovarian cancer is unacceptably low.
Pratibha S. Binder +9 more
doaj +1 more source
James M. Buchanan’s contractarianism and modern liberalism [PDF]
Constitutional Political Economy, 2014 This paper contrasts Buchanan’s contractarian–constitutional liberalism with Hayek’s evolutionary liberalism and Rothbards free-market liberalism as representative branches of the classical liberal tradition. While Hayek and Rothbard focus on individual liberty as private autonomy, Buchanan posits that individual sovereignty should be recognized as the
openaire +2 more sources
The Prostate, EarlyView.ABSTRACT Background Methyl Methanesulfonate‐Sensitivity Protein 22‐Like (MMS22L) plays a key role in homology‐directed DNA repair, and experimental models have shown that its loss confers sensitivity to Poly (ADP‐ribose) polymerase inhibitors (PARPi).
Mayuko Kanayama +12 more
wiley +1 more source
Frontiers in Marine Science, 2022 The mass of well-preserved calcite in planktonic foraminifera shells provides an indication of the calcification potential of the surface ocean. Here we report the shell weight of 8 different abundant planktonic foraminifera species from a set of core ...
Stergios D. Zarkogiannis +8 more
doaj +1 more source
La filosofía económica de James M. Buchanan [PDF]
, 2011 Starting from the assumptions of methodological individualism, ‘homo economicus’ and the modeling of politics as exchange, Buchanan develops contractual and constitutional bases for the theory of economic and political decision making. For him, knowledge
Casas, J. (José)
core
Buchanan and the Social Contract: Coordination Failures and the Atrophy of Property Rights
Southern Economic Journal, EarlyView.ABSTRACT James Buchanan advocated that societies should be based on a social contract. He rejected anarchy, seeing it as a “Hobbesian jungle” that calls for government intervention to maintain social order. He also opposed theories of spontaneous order. These views led to debates about the compatibility of Buchanan's works with classical liberalism and
Stefano Dughera, Alain Marciano
wiley +1 more source
Translational Psychiatry, 2022 Social cognitive impairments are core features of schizophrenia spectrum disorders (SSD) and are associated with greater functional impairment and decreased quality of life.
Sunny X. Tang +9 more
doaj +1 more source