Results 21 to 30 of about 817,896 (162)

AusTraits, a curated plant trait database for the Australian flora

open access: yesScientific Data, 2021
Measurement(s) plant trait Technology Type(s) digital curation Sample Characteristic - Organism Viridiplantae Sample Characteristic - Location Australia Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare ...
Daniel Falster   +217 more
doaj   +1 more source

The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

open access: yesiScience, 2021
Summary: We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of ...
Thushan I. de Silva   +1012 more
doaj   +1 more source

A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry

open access: yesBreast Cancer Research, 2023
Background Genome-wide studies of gene–environment interactions (G×E) may identify variants associated with disease risk in conjunction with lifestyle/environmental exposures.
Pooja Middha   +134 more
doaj   +1 more source

Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial

open access: yesContemporary Clinical Trials Communications, 2021
Introduction: Pragmatic trials in comparative effectiveness research assess the effects of different treatment, therapeutic, or healthcare options in clinical practice.
David Pogorzelski   +384 more
doaj   +1 more source

Management and early outcomes of children with appendicitis in the UK and Ireland during the COVID-19 pandemic: a survey of surgeons and observational study

open access: yesBMJ Paediatrics Open, 2020
Objectives Acute appendicitis is the most common surgical condition in children. In the UK, appendicectomy is the most common treatment with non-operative management unusual.
Nigel J Hall   +190 more
doaj   +1 more source

Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials

open access: yesContemporary Clinical Trials Communications, 2021
Introduction: Cluster randomized crossover trials are often faced with a dilemma when selecting an optimal model of consent, as the traditional model of obtaining informed consent from participant's before initiating any trial related activities may not ...
Guillermo Pechero, Jr., MD   +399 more
doaj   +1 more source

Encountering China: the evolution of Timothy Richard's missionary thought (1870-1891) [PDF]

open access: yes, 2019
In pursuit of the conversion of others, cross-cultural missionaries often experience their own “conversions.” This thesis explores the ways in which one particular missionary, the Welshman Timothy Richard (1845–1919), was transformed by his encounter ...
Ireland, Daryl
core  

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +15 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Multimodal Mass Spectrometry Imaging of an Osteosarcoma Multicellular Tumour Spheroid Model to Investigate Drug-Induced Response

open access: yesMetabolites
A multimodal mass spectrometry imaging (MSI) approach was used to investigate the chemotherapy drug-induced response of a Multicellular Tumour Spheroid (MCTS) 3D cell culture model of osteosarcoma (OS). The work addresses the critical demand for enhanced
Sophie M. Pearce   +9 more
doaj   +1 more source

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