Results 1 to 10 of about 2,887,032 (135)
Ethnic and social inequalities in COVID-19 outcomes in Scotland: protocol for early pandemic evaluation and enhanced surveillance of COVID-19 (EAVE II). [PDF]
BMJ Open, 2021 Introduction Evidence from previous pandemics, and the current COVID-19 pandemic, has found that risk of infection/severity of disease is disproportionately higher for ethnic minority groups, and those in lower socioeconomic positions.Henery P, Vasileiou E, Hainey KJ, Buchanan D, Harrison E, Leyland AH, Alexis T, Robertson C, Agrawal U, Ritchie L, Stock SJ, McCowan C, Docherty A, Kerr S, Marple J, Wood R, Moore E, Simpson CR, Sheikh A, Katikireddi SV. +19 moreeuropepmc +2 more sourcesEffects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model
Physiological Reports, Volume 11, Issue 15, August 2023., 2023 Hypoxic ischemic encephalopathy (HIE) occurs in 2–5/1000 births, with acute kidney injury (AKI) occurring in 40%. AKI increases morbidity and mortality.A. Groves, C. Johnston, G. Beutner, J. Dahlstrom, M. Koina, M. O’Reilly, B. Marples, G. Porter, P. Brophy, A. Kent +9 moresemanticscholar +2 more sourcesChanges in intra- and interlimb reflexes from hindlimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats. [PDF]
J PhysiolAbstract figure legend Contacting an obstacle during locomotion activates cutaneous afferents to maintain balance and coordinate all four limbs. Spinal cord injuries disrupt neural communications between spinal networks controlling the fore‐ and hindlimbs, impairing balance and limb coordination.Mari S, Lecomte CG, Merlet AN, Audet J, Yassine S, Eddaoui O, Genois G, Nadeau C, Harnie J, Rybak IA, Prilutsky BI, Frigon A. +11 moreeuropepmc +2 more sourcesInterim findings from first-dose mass COVID-19 vaccination roll-out and COVID-19 hospital admissions in Scotland: a national prospective cohort study
The Lancet, 2021 Summary Background The BNT162b2 mRNA (Pfizer–BioNTech) and ChAdOx1 nCoV-19 (Oxford–AstraZeneca) COVID-19 vaccines have shown high efficacy against disease in phase 3 clinical trials and are now being used in national vaccination programmes in the UK and ...E. Vasileiou, Colin Simpson, T. Shi, S. Kerr, U. Agrawal, A. Akbari, S. Bedston, J. Beggs, D. Bradley, A. Chuter, S. de Lusignan, A. Docherty, D. Ford, F. Hobbs, M. Joy, S. Katikireddi, James Marple, C. McCowan, D. McGagh, J. McMenamin, E. Moore, J. Murray, Jiafeng Pan, L. Ritchie, S. A. Shah, S. Stock, F. Torabi, R. Tsang, R. Wood, M. Woolhouse, C. Robertson, A. Sheikh +31 moresemanticscholar +1 more sourceImpact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales
BMC Medicine, 2021 Background The COVID-19 pandemic and ensuing national lockdowns have dramatically changed the healthcare landscape. The pandemic’s impact on people with chronic obstructive pulmonary disease (COPD) remains poorly understood.Mohammad A. Alsallakh, Shanya Sivakumaran, S. Kennedy, E. Vasileiou, R. Lyons, C. Robertson, Aziz Sheikh, G. Davies, Colin R. Jim Lewis D. Mark Helen R. Diogo Josie Sarah Ra Simpson McMenamin Ritchie Woolhouse Stagg Marques , Colin Simpson, J. McMenamin, L. Ritchie, M. Woolhouse, H. Stagg, D. Marques, J. Murray, S. Stock, R. Wood, C. McCowan, U. Agrawal, A. Docherty, Rachel H. Mulholland, E. Moore, James Marple, Vicky Hammersley +24 moresemanticscholar +1 more sourceEffectiveness of First Dose of COVID-19 Vaccines Against Hospital Admissions in Scotland: National Prospective Cohort Study of 5.4 Million People
Social Science Research Network, 2021 Background: The BNT162b2 mRNA (Pfizer-BioNTech) and ChAdOx1 (Oxford-AstraZeneca) COVID-19 vaccines have demonstrated high efficacy against infection in phase 3 clinical trials and are now being used in national vaccination programmes in the UK and ...E. Vasileiou, Colin Simpson, C. Robertson, T. Shi, S. Kerr, U. Agrawal, A. Akbari, S. Bedston, J. Beggs, D. Bradley, A. Chuter, S. de Lusignan, A. Docherty, D. Ford, R. Hobbs, M. Joy, S. Katikireddi, James Marple, C. McCowan, D. McGagh, J. McMenamin, E. Moore, J. Murray, Jiafeng Pan, L. Ritchie, S. A. Shah, S. Stock, F. Torabi, R. Tsang, R. Wood, M. Woolhouse, A. Sheikh +31 moresemanticscholar +1 more sourceFirst dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and Wales
PLoS Medicine, 2022 Background Several countries restricted the administration of ChAdOx1 to older age groups in 2021 over safety concerns following case reports and observed versus expected analyses suggesting a possible association with cerebral venous sinus thrombosis ...S. Kerr, M. Joy, F. Torabi, S. Bedston, A. Akbari, U. Agrawal, J. Beggs, D. Bradley, A. Chuter, A. Docherty, D. Ford, R. Hobbs, S. Katikireddi, E. Lowthian, S. de Lusignan, R. Lyons, James Marple, C. McCowan, D. McGagh, J. McMenamin, E. Moore, J. Murray, R. Owen, Jiafeng Pan, L. Ritchie, S. A. Shah, T. Shi, S. Stock, R. Tsang, E. Vasileiou, M. Woolhouse, Colin Simpson, C. Robertson, Aziz Sheikh +33 moresemanticscholar +1 more sourceUse of Angiotensin Converting Enzyme Inhibitors is Associated with Reduced Risk of Late Bladder Toxicity Following Radiotherapy for Prostate Cancer.
Radiotherapy and Oncology, 2022 BACKGROUND AND PURPOSE
Genome-wide association studies (GWAS) of late hematuria following prostate cancer radiotherapy identified single nucleotide polymorphisms (SNPs) near AGT, encoding angiotensinogen.S. Kerns, Ashley Amidon Morlang, Sharon Lee, Derick R. Peterson, B. Marples, Hong Zhang, K. Bylund, D. Rosenzweig, W. Hall, K. De Ruyck, B. Rosenstein, R. Stock, A. Gómez-Caamaño, A. Vega, Paloma Sosa-Fajardo, B. Taboada-Valladares, Miguel E. Aguado-Barrera, C. Parker, L. Veldeman, V. Fonteyne, Renée Bultijnck, C. Talbot, R. Paul Symonds, Kerstie Johnson, T. Rattay, A. Webb, M. Lambrecht, D. de Ruysscher, B. Vanneste, A. Choudhury, R. Elliott, E. Sperk, C. Herskind, M. Veldwijk, T. Rancati, B. Avuzzi, R. Valdagni, D. Azria, Marie-Pierre Farcy Jacquet, J. Chang-Claude, P. Seibold, C. West, M. Janelsins, Yuhchyau Chen, E. Messing, G. Morrow, E. Briers, A. Dunning, R. Elliott, S. Gutiérrez‐Enríquez, T. Rancati, T. Rattay, B. Rosenstein, D. de Ruysscher, E. Sperk, R. Paul Symonds, H. Stobart, C. Talbot, A. Vega, L. Veldeman, Tim E. Ward, A. Webb, C. West +62 moresemanticscholar +1 more sourceCharacterisation of the onset and severity of adrenal and thyroid dysfunction associated with CTLA4-related hypophysitis.
European Journal of Endocrinology, 2021 CONTEXT
Use of the CTLA4 inhibitor, ipilimumab, has proven efficacious in treatment of melanoma, renal carcinoma and non-small cell lung cancer, however, is associated with frequent immune-related adverse events (irAE).K. Seejore, Marilena Giannoudi, Djoah Osborn, J. Lynch, Ahmed Al-Qaissi, E. Dunwoodie, J. Hook, M. Marples, R. Murray +8 moresemanticscholar +1 more sourceClimate change drives habitat contraction of a nocturnal arboreal marsupial at its physiological limits
Ecosphere, Volume 11, Issue 10, October 2020., 2020 Abstract
Increasing impacts of climatic change and anthropogenic disturbances on natural ecosystems are leading to population declines or extinctions of many species worldwide. In Australia, recent climatic change has caused population declines in some native fauna.Benjamin Wagner, Patrick J. Baker, Stephen B. Stewart, Linda F. Lumsden, Jenny L. Nelson, Jemma K. Cripps, Louise K. Durkin, Michael P. Scroggie, Craig R. Nitschke +8 morewiley +1 more source