Results 11 to 20 of about 2,887,032 (135)

The Body in the Library: An investigative celebration of deviation, hesitation, and lack of closure [PDF]

, 2018
The unexpected, if still clichéd, discovery of a body in the library introduces Agatha Christie’s plot starring the genius amateur detective, elderly Miss Marple.
Kociatkiewicz, J., Kostera, M.
core   +3 more sources

Complications of bone metastases from malignant melanoma

Journal of Bone Oncology, 2017
Introduction Metastatic bone disease (MBD) carries significant morbidity for patients with cancer. MBD from malignant melanoma (MM) is understudied. We examined the characteristics, morbidity, management and outcome of MBD in patients with MM.
J. Zekri, M. Marples, Dominic M. Taylor, K. Kandukurti, L. McParland, Janet E Brown   +5 more
semanticscholar   +1 more source

Adjuvant bevacizumab in patients with melanoma at high risk of recurrence (AVAST-M): preplanned interim results from a multicentre, open-label, randomised controlled phase 3 study.

The Lancet Oncology, 2014
BACKGROUND Bevacizumab, a monoclonal antibody that targets VEGF, has shown restricted activity in patients with advanced melanoma. We aimed to assess the role of bevacizumab as adjuvant treatment for patients with resected melanoma at high risk of ...
P. Corrie, A. Marshall, J. Dunn, M. Middleton, P. Nathan, M. Gore, N. Davidson, S. Nicholson, C. Kelly, M. Marples, S. Danson, E. Marshall, S. Houston, R. Board, A. Waterston, J. Nobes, M. Harries, Satish B. Kumar, G. Young, P. Lorigan   +19 more
semanticscholar   +1 more source

“The Crime Scene as Museum: The (Re)construction in the Bresciano Series of a Historical Gibraltarian Past” [PDF]

, 2016
The “Bresciano” series of seven historical detective novels (2010-2015) by Sam Benady and Mary Chiappe set in a period of four decades early in the British imperial history of Gibraltar from the 1780s to the 1820s provides an excellent opportunity not ...
Stotesbury, John
core   +3 more sources

Adjuvant bevacizumab for melanoma patients at high risk of recurrence: survival analysis of the AVAST-M trial

Annals of Oncology, 2019
Background: is a recombinant humanised monoclonal antibody to vascular endothelial growth factor shown to improve survival in advanced solid cancers. We evaluated the role of adjuvant bevacizumab in melanoma patients at high risk of recurrence.
P. Corrie, A. Marshall, P. Nathan, P. Lorigan, M. Gore, S. Tahir, G. Faust, C. Kelly, M. Marples, S. Danson, E. Marshall, S. Houston, R. Board, A. Waterston, J. Nobes, M. Harries, S. Kumar, A. Goodman, A. Dalgleish, A. Martín-Clavijo, S. Westwell, R. Casasola, D. Chao, A. Maraveyas, P. Patel, C. Ottensmeier, D. Farrugia, A. Humphreys, B. Eccles, G. Young, E. Barker, C. Harman, M. Weiss, K. Myers, A. Chhabra, S. Rodwell, J. Dunn, M. Middleton   +37 more
semanticscholar   +2 more sources

Adjuvant bevacizumab for melanoma patients at high risk of recurrence: survival analysis of the AVAST-M trial

Annals of Oncology, 2018
Background Bevacizumab is a recombinant humanised monoclonal antibody to vascular endothelial growth factor shown to improve survival in advanced solid cancers. We evaluated the role of adjuvant bevacizumab in melanoma patients at high risk of recurrence.
P. Corrie, A. Marshall, P. Nathan, P. Lorigan, M. Gore, S. Tahir, G. Faust, C. Kelly, M. Marples, S. Danson, E. Marshall, S. Houston, R. Board, A. Waterston, J. Nobes, M. Harries, S. Kumar, A. Goodman, A. Dalgleish, A. Martín-Clavijo, S. Westwell, R. Casasola, D. Chao, A. Maraveyas, P. Patel, C. Ottensmeier, D. Farrugia, A. Humphreys, B. Eccles, G. Young, E. Barker, C. Harman, M. Weiss, K. Myers, A. Chhabra, S. Rodwell, J. Dunn, M. Middleton, Paul Paul Peter Sonja Udaiveer Saad Guy Anne Pippa Bhaw Nathan Lorigan Dziewulski Holikova Panwar Tahir Fa, P. Nathan, P. Lorigan, P. Dziewulski, Sonja Holikova, U. Panwar, S. Tahir, G. Faust, Anne L. Thomas, P. Corrie, B. Sirohi, C. Kelly, M. Middleton, M. Marples, S. Danson, J. Lester, E. Marshall, M. Ajaz, S. Houston, R. Board, D. Eaton, A. Waterston, J. Nobes, Suat Loo, Gill Gray, H. Stubbings, M. Gore, M. Harries, Satish B. Kumar, A. Goodman, A. Dalgleish, A. Martín-Clavijo, J. Marsden, S. Westwell, R. Casasola, D. Chao, A. Maraveyas, P. Patel, C. Ottensmeier, D. Farrugia, A. Humphreys, B. Eccles, Renata Dega, C. Herbert, C. Price, M. Brunt, M. Scott-Brown, Joanna M. Hamilton, R. L. Hayward, J. Smyth, P. Woodings, N. Nayak, L. Burrows, V. Wolstenholme, J. Wagstaff, M. Nicolson, Andrew D. Wilson, C. Barlow, C. Scrase, T. Podd, Michael Gonzalez, J. Stewart, M. Highley, S. Grumett, T. Talbot, K. Nathan, R. Coltart, B. Gee   +105 more
semanticscholar   +1 more source

Cosmopolitan nationalism and the cultural reach of the white British [PDF]

, 2010
In recent years, strong claims have been made for the breakdown of national boundaries and the reformation of national identities in an increasingly interconnected global world – driven in large part by the possibilities and limitations that emerge from ...
Albrow, Aldridge, Anderson, Appadurai, Augé, Back, Benjamin, Bennett, Billig, Bourdieu, Breuilly, Calhoun, Calhoun, Calhoun, Castells, Cinnirella, Cinnirella, Cohen, Condor, Cram, Gilroy, Gilroy, Hearn, Hoggart, Holt, Huntington, Hutchinson, Jacobson, Kalra, Kumar, Langlands, McCrone, Ong, Papastergiadis, Robertson, Said, Savage, Savage, Smith, Smith, Smith, Stevenson, Tyler, Wright   +43 more
core   +1 more source

Arginase‐II negatively regulates renal aquaporin‐2 and water reabsorption

The FASEB Journal, Volume 32, Issue 10, Page 5520-5531, October 2018., 2018
ABSTRACT Type‐II L‐arginine:ureahydrolase, arginase‐II (Arg‐II), is abundantly expressed in the kidney. The physiologic role played by Arg‐II in the kidney remains unknown. Herein, we report that in mice that are deficient in Arg‐II (Arg‐II−/−), total and membrane‐associated aquaporin‐2 (AQP2) protein levels were significantly higher compared with wild‐
Ji Huang, Jean‐Pierre Montani, François Verrey, Eric Feraille, Xiu‐Fen Ming, Zhihong Yang   +5 more
wiley   +1 more source

The Decay of Communism: Managing Spent Nuclear Fuel in the Soviet Union, 1937‐1991

Risk, Hazards &Crisis in Public Policy, Volume 1, Issue 4, Page 83-109, November 2010., 2010
Abstract The aim of this article is to explore the dynamics of spent nuclear fuel management in the Soviet Union, from the origins of nuclear engineering in the 1930s to the collapse of the country in 1991. Spent nuclear fuel is analyzed in relation to other components of what is referred to as the “nuclear fuel system,” such as nuclear weapons ...
Per Högselius
wiley   +1 more source

MON-290 Ipilimumab Immune-Related ACTH Deficiency Is of Acute Onset and Severe

Journal of the Endocrine Society, 2020
Introduction Immune checkpoint inhibitors (ICIs) are immunomodulatory molecules that downregulate T-cell inhibiting-receptors or ligands to promote an enhanced anti-tumour response.
K. Seejore, Marilena Giannoudi, Djoah Osborn, J. Lynch, Elaine Dunwoodie, Jane Hook, M. Marples, Robert D Murray   +7 more
semanticscholar   +1 more source