Results 151 to 160 of about 126,361 (307)

The Rear Window of Essentialism

Film-Philosophy, 1997
Lazslo Tarnay
doaj   +1 more source

Janus

, 1993
Janus is a high-level procedural programming language. It was designed and implemented to be an introductory language for children aged seven to eleven. Janus is a computer language that is graphic-based. A key feature of this language is turtle graphics
Marty, Mary Lou A., Valenzuela, Vida B., Jumig, Judith C., Banzon, Emilio F.   +3 more
core  

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Therapeutic effects of janus kinase inhibitors

Janus kinase (JAK) inhibitors are small synthetic molecules which can easily enter the intracellular space and inhibit janus kinases, which renders the janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway to be nonfunctional.
Ntwali, Arnaud
core  

From brush conformation to 3D Supraparticles: Programmable self‐assembly of polymer‐grafted nanoparticles in emulsion confinement

Bulletin of the Korean Chemical Society, EarlyView.
This review highlights how the conformational adaptability of polymer‐grafted nanoparticles drives their programmable self‐assembly within 3D emulsion droplets. By coupling brush thermodynamics with soft confinement, these dynamic building blocks form hierarchical supraparticles tailored for advanced plasmonics, compartmentalized catalysis, and stimuli‐
Hongseok Yun
wiley   +1 more source

DFT investigation of Na-ion interaction with Janus 1T-HfSTe monolayer for sodium-ion battery anodes. [PDF]

Nanoscale Adv
Pham KD, Hoang DQ, Tong HD, Ho TH, Vu TV.   +4 more
europepmc   +1 more source

Janus revisited

Academic Medicine, 1967
openaire   +3 more sources

adiecta est Henrici Christophori Schlichtegrullii ... Disputatio extemporalis, V. die studiorum scripta, etc

Bogensignaturen: A ...
Crucis, Janus
core   +1 more source