Results 51 to 60 of about 4,408,063 (301)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Annual Report on the Environment in Japan

open access: yes, 2009
The white paper on comprehensive environmental policy describes the role of Japan's economy in a sound global environment. In the first part, the report describes current the environmental conditions of the Earth and of Japan, human activities in Japan ...
[Japan] Ministry of the Environment
core  

National greenhouse gas inventory document of Japan. 2025 (CGER-report ; CGER-I174-2025) [PDF]

open access: yes
content reviewed by Decarbonized Society Promotion Office, Global Environment Bureau, Ministry of the Environment, Japan primary authors Greenhouse Gas Inventory Office of Japan, Center for Global Environmental Research, Earth System Division, National ...
Greenhouse Gas Inventory Office of Japan (GIO)
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

1:500,000 geological map [cartographic material] : [Japan] /

open access: yes, 1951
Geological map series of Japan. Relief shown by spot heights.; Published in various eds.; Sheets published prior to approximately the mid-1970s do not have a series title, only a sheet title.One to five hundred thousand geological ...
Chishitsu Chosajo (Japan)
core  

Destructive discourse: 'Japan-bashing' in the United States, Australia and Japan in the 1980s and 1990s [PDF]

open access: yes, 2006
By the 1960s-70s, most Western commentators agreed that Japan had rehabilitated itself from World War II, in the process becoming on the whole a reliable member of the international community.
Morris, Narrelle
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

[Japan 1:1,000,000] [cartographic material] /

open access: yes, 1966
various eds. Relief shown by gradient tints, contours, shading, and spot heights. Depths shown by gradient tints, contours, and soundings.; In upper left margin: 1:1,000,000 kokusaizu = Carte internationale du monde au 1:1,000,000.; Includes notes and ...
Kokudo Chiriin (Japan)
core  

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