Results 81 to 90 of about 5,013 (193)
Background: Genetic and environmental factors are proposed to be involved in cedar pollen allergy sensitization and onset. The impact of these factors will provide key information for the prevention of cedar pollen sensitization and allergy onset, which ...
Satoshi Nakamura +5 more
doaj +1 more source
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova +6 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Background: IgG antibody to allergens in the serum of pollinosis patients is not routinely measured, because there are no simple methods for assaying small amounts of specific IgG in the serum ; so far only IgE and IgG4 antibodies have been assayed.
Hiroshi Miyazawa +6 more
doaj +1 more source
Nationwide Survey of Atopic Myelitis and Plexin D1‐Immunoglobulin G‐Related Pain
ABSTRACT Objective To elucidate the features of plexin D1‐immunoglobulin (Ig)G‐associated neuropathic pain and its relationship to atopic myelitis (AM) in a nationwide Japanese survey. Methods A preliminary survey questionnaire was sent to 1574 selected departments (neurology and pediatrics/pediatric neurology) to explore the numbers of AM and plexin ...
Jun‐ichi Kira +10 more
wiley +1 more source
Are Respiratory Viruses Involved in Preseasonal Symptoms or Severity in Japanese Cedar Pollinosis?
Background Respiratory virus infections are involved in asthma exacerbations. However, there are no reports of the relationship between respiratory virus infections and Japanese cedar pollinosis.
Hirokuni Otsuka M.D. +4 more
doaj +1 more source
Background: Recent studies have suggested that allergic rhinitis is closely related to bronchial asthma, reflecting the "one airway-one disease" hypothesis.
Hironori Sagara +4 more
doaj +1 more source
Conceptual diagram of hydrological and geochemical processes within the Santa Elena Ophiolite, Costa Rica. It highlights watershed cross‐sections, soil genesis, hyperalkaline Type II waters (pH > 11.6) with calcite crust and trapped H2/CH4 gases, seepage into surface waters, storm‐impacted stream profiles, weathered vs.
Alexandra May +8 more
wiley +1 more source
We developed a fluorometric enzyme-linked immunosorbent assay (ELISA) for allergen-specific IgE in dogs with the use of monoclonal anti-dog IgE; we assayed IgE antibody to Japanese cedar pollen in the sera of dogs with Japanese cedar pollinosis.
Masahiro Sakaguchi +5 more
doaj +1 more source
We demonstrated a new approach for estimating fine‐scale 3‐dimensional (3D) visibility based on single scans from a terrestrial laser scanner. Our method produced results that were comparable to traditional 2D visibility estimates assessed with profile boards but provides comprehensive information across all directions and continuous distances ...
Rachel M. Stein +5 more
wiley +1 more source

