Background: Epinastine hydrochloride and fexofenadine hydrochloride, the second-generation antihistamines, are largely used in the indication of allergic rhinitis in Japan.
Kimihiro Okubo, Minoru Gotoh
doaj +1 more source
Detection of New Antigenic Proteins in Japanese Cedar Pollen
In Japan, an increasing number of people suffer from pollenosis, a typical atopic disease. Japanese cedar (Cryptomeria japonica) pollen is the most common allergen that causes pollenosis. Although Cry j 1 and Cry j 2 are the common allergenic proteins contained in the pollen, there is a small population of patients who exhibit positive skin reactions ...
Matsumura, Daichi +4 more
openaire +3 more sources
Terminal settling velocity and physical properties of pollen grains in still air [PDF]
Numerical simulation of wind pollination requires knowledge of pollen grain physical parameters such as size, shape factor, bulk density, and terminal settling velocity.
Hirose, Yuuki, Osada, Kazuo
core +1 more source
Tree Pollen Sensitization and Cross-Reaction of Children with Allergic Rhinitis or Asthma [PDF]
Objectives Tree pollen causes allergic rhinitis and asthma. We investigated children who diagnosed as rhinitis or asthma, living in Busan, for tree allergen sensitization, component allergen, oral allergy syndrome, and the relationship between pollen ...
Ye Jin Park, Yoon Ha Hwang
doaj +1 more source
Hypersensitivity to Japanese Cedar (Cryptomeria japonica) Pollen in Dogs.
Four of 51 dogs with chronic dermatitis were made to react to crude Japanese cedar (Cryptomeria japonica, CJ) pollen allergen by the intradermal skin test (IDST). These four dogs had specific IgE to CJ as determined by Prausnitz-Küstner test. In the provocation test, nasal discharge increased 5 to 20 min after introduction of the crude CJ pollen ...
SASAKI, Yoshihide +6 more
openaire +3 more sources
Evaluating the Effects of Testing Period on Pollinosis Symptoms Using an Allergen Challenge Chamber
Background: We previously built a pollen challenge test unit (allergen challenge chamber: ACC) to collect objective data about Japanese cedar pollinosis. In this study, we investigated adequate conditions for pollen challenge using the ACC.
Ayumi Yuki +6 more
doaj +1 more source
Intranasal exposure to monoclonal antibody Fab fragments to Japanese cedar pollen Cry j1 suppresses Japanese cedar pollen‐induced allergic rhinitis [PDF]
Background and PurposeFab fragments (Fabs) of antibodies have the ability to bind to specific allergens but lack the Fc portion that exerts effector functions via binding to receptors including FcεR1 on mast cells. In the present study, we investigated whether intranasal administration of the effector function‐lacking Fabs of a monoclonal antibody IgG1
S, Yoshino, N, Mizutani
openaire +2 more sources
Pollen food allergy syndrome (PFAS) is caused by cross-reactivity with pollen; however, not all-pollen-sensitised individuals develop PFAS, and studies on the characteristics of PFAS development are limited in Japan.
Masaya Kato +6 more
doaj +1 more source
The incidence of Japanese cedar pollinosis and sensitization to the pollen allergens among Japanese monkeys in a troop [PDF]
The natural occurrence of Japanese cedar (Cryptomeria japonica; CJ) pollinosis has been reported in Japanese monkeys (Macaca fuscata), an appropriate animal model for developing antipollinosis therapies. However, there has been no study on the incidence of Japanese cedar pollinosis in monkeys.
M, Sakaguchi +8 more
openaire +4 more sources
Prevalence of inhaled allergen-specific IgE antibody positivity in the healthy Japanese population
Background: Measurement of allergen-specific IgE antibodies to inhaled allergens is important for the diagnosis and risk evaluation of allergic diseases such as asthma and allergic rhinitis.
Jun Tanaka +9 more
doaj +1 more source

