A Randomized Double-Blind Comparative Study of Sublingual Immunotherapy for Cedar Pollinosis [PDF]
Background: Seasonal allergic rhinitis (SAR) induced by Japanese cedar pollen is a substantial problem in Japan. Sublingual immuno-therapy (SLIT) is safer than conventional antigen-specific immunotherapy, the only treatment modality by which complete ...
Kimihiro Okubo +8 more
doaj +2 more sources
Effects of Pranlukast Hydrate on Airway Hyperresponsiveness in Non-Asthmatic Patients with Japanese Cedar Pollinosis [PDF]
Background: Recent studies have suggested that allergic rhinitis is closely related to bronchial asthma, reflecting the "one airway-one disease" hypothesis.
Hironori Sagara +4 more
doaj +2 more sources
Real-world efficacy of sublingual immunotherapy with Japanese cedar pollen for cypress pollinosis [PDF]
Background: It remains unclear whether allergen immunotherapy with Japanese cedar pollen extract is effective for Japanese cypress pollinosis in real-world settings. Objective: We sought to investigate the Japan-wide prevalence of cypress pollinosis, the
Aiko Oka, MD +37 more
doaj +2 more sources
Intake of a fermented plant product attenuates allergic symptoms without changing systemic immune responses in a mouse model of Japanese cedar pollinosis [PDF]
Background Japanese cedar pollinosis (JCP) is one of the most prevalent allergies in Japan. Within the past few decades, many food factors have been demonstrated to suppress symptoms of pollinosis and mast cell degranulation directly or indirectly ...
Takashi Fujimura +5 more
doaj +2 more sources
Therapeutic effect of bilastine in Japanese cedar pollinosis using an artificial exposure chamber (OHIO Chamber) [PDF]
Background: Environmental exposure chambers have been used to expose subjects to aeroallergens to investigate the efficacy of prophylactic treatment with symptomatic agents in Japan.
Kazuhiro Hashiguchi +4 more
doaj +2 more sources
Background: About one-third of the Japanese population suffers from Japanese cedar pollinosis, which is frequently accompanied by Japanese cypress pollinosis. Recently, a novel major Japanese cypress pollen allergen, Cha o 3, was discovered.
Toshihiro Osada +4 more
doaj +2 more sources
Measurement of Japanese Cedar Pollen-Specific IgE in Nasal Secretions [PDF]
Background: : Japanese cedar pollen (JCP) is the most common allergen for seasonal allergic rhinitis in Japan. Little is known about local production of immunoglobulin (Ig)E in people with or without Japanese cedar pollinosis. The aims of this study were
Hiroshi Sakaida +2 more
doaj +2 more sources
Safety and efficacy of a new regimen of short-term oral immunotherapy with Cry j 1-galactomannan conjugate for Japanese cedar pollinosis: A prospective, randomized, open-label study [PDF]
Background: Short-term oral immunotherapy (OIT) using the Cry j1-galactomannan conjugate for Japanese cedar pollinosis may be effective and relatively safe. However, a treatment regimen has not been established.
Daisuke Murakami +6 more
doaj +2 more sources
Analysis of Helper T Cell Responses to Cry j 1-Derived Peptides in Patients with Nasal Allergy: Candidate for Peptide-Based Immunotherapy of Japanese Cedar Pollinosis [PDF]
Background: Allergen specific immunotherapy is highly effective, but adverse events may occur during treatment. Peptide-based immunotherapy has been proposed as one of new strategies for reduction of allergic adverse reactions.
Keisuke Masuyama +6 more
doaj +2 more sources
Early Interventional Treatment with Intranasal Mometasone Furoate in Japanese Cedar/Cypress Pollinosis: A Randomized Placebo-Controlled Trial [PDF]
Background: Little is known about the safety and effectiveness of early interventional treatment (EIT) with intranasal corticosteroids for seasonal allergic rhinitis.
Seiichiro Makihara +9 more
doaj +2 more sources

