Results 51 to 60 of about 5,643,181 (379)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Personal Values of Japanese Business Managers [PDF]

open access: yes, 1999
Researchers have spent many years examining the Japanese business culture, but there is limited empirical evidence about the personal values of Japanese business managers.
Akers, Michael D.   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Open source, collectivism, and Japanese society [PDF]

open access: yes, 2010
This paper is about collectivism in the Network Society. Many\ud researches about the Network Society evaluate collectivism, citing Japanese\ud culture and Hacker culture as good models of such collectivism. However, some\ud researchers, such as K.
Iitaka, Toshikazu
core  

The Erotic and the Vulgar: Visual Culture and Organized Labor's Critique of U.S. Hegemony in Occupied Japan [PDF]

open access: yes, 2007
This essay engages the colonial legacy of postwar Japan by arguing that the political cartoons produced as part of the postwar Japanese labor movement’s critique of U.S.
Allison Anne   +51 more
core   +1 more source

Japanese Traditional Miso and Koji Making

open access: yesJournal of Fungi, 2021
Miso is a traditional Japanese seasoning paste produced by fermenting soybeans using the power of koji mold. A recent Japanese cohort study has shown that increased consumption of fermented soybean products is associated with a reduced risk of death in ...
K. Kusumoto   +6 more
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

'Thinking of Spain in a flat way:' visiting Spain and Spanish cultural heritage through contemporary Japanese anime [PDF]

open access: yes, 2017
This article contextualizes the representation of Spain and Spanish culture among Japanese cultural producers, particularly through the production of Japanese commercial animation (commonly named anime).
Hernandez-Perez, Manuel
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

[Review of] Joseph J. Tobin, ed. Re-made in Japan: Everyday Life and Consumer Taste in a Changing Society [PDF]

open access: yes, 1993
The introduction\u27s title to Re-made in Japan, Domesticating the West, captures precisely the characteristics of the contemporary westernization of Japanese culture.
Takahara, Kumiko
core   +1 more source

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