Results 91 to 100 of about 1,409,358 (310)

They Were the First: Remembering the Creators of Post-War Japanese Fashion

open access: yesЕжегодник Япония
The article is devoted to the recently deceased outstanding Japanese fashion designers, Mori Hanae, Takada Kenzo and Miyake Issey, who can rightfully be called pioneers of post-war Japanese fashion.They not only created a cultural phenomenon based on the
E. L. Katasonova
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

The Encoding of Emotions in Ogawa Yōko’s Works: Sensory Narration and Mood Tableaux

open access: yesJapanese Language and Literature
The present article investigates in what way emotions are encoded in the works of Yōko Ogawa and reveals how their potential impact on affect and feelings unfolds. It argues that emotions predominantly occur in their pre-reflective form, i.e.
Elena Giannoulis
doaj   +1 more source

The legacy of the Kamon in the Japanese management [PDF]

open access: yes
Japan in itself but especially after the so-called “Japanese miracle” generated a frenzy of questions that searched for the hidden secret recipe for economic growth.
Costache Sorina, Opreanu Bogdan
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Executive Compensation in Japan: Estimating Levels and Determinants from Tax Records [PDF]

open access: yes
Most studies of executive compensation have data on pay but not total income. Because exchange-listed Japanese firms (unlike exchange-listed U.S. firms) need not disclose executive compensation figures in their securities filings, most studies on Japan ...
Eric Rasmusen   +2 more
core  

A quantitative history of Japanese archaeology and natural science [PDF]

open access: yes, 2018
This study examines the relationship between Japanese archaeology and natural science through a quantitative analysis of the two most authoritative archaeological journals and two other relevant journals in Japan.
Nakao, Hisashi
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Factors Influencing Economic Integration in East Asia During 1980-2012 Considering the Role of Japan [PDF]

open access: yesFaslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2015
The spread of high economic growth among East Asian countries in the last three decades resulted in increasing attention regarding these countries’ development models.
Nahid Pour-Rostami
doaj  

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