Results 51 to 60 of about 1,403,331 (309)

Continental Policy of Japan as Seen From France: Indochina Crisis of 1940 and Politicians of the Vichy Regime (Part Two)

open access: yesЕжегодник Япония, 2023
The present work, consisting of two parts, deals with the little-studied aspects of the Indochina crisis of 1940 in Japanese–French relations – Japan’s claims to control and military presence in French Indochina in the summer and autumn of 1940.
V. E. Molodiakov
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Transmitting the Body: Benjamin Hobson, Quanti Xinlun, and the Dawn of Western Anatomy in China

open access: yesReligions
This study focuses on Quanti Xinlun (1851), translated and compiled by the Protestant missionary Benjamin Hobson in the late Qing dynasty, examining how the Western anatomical knowledge it introduced challenged and reshaped the traditional Chinese ...
Shuang Ma, Ningjun Li, Wenwei Mao
doaj   +1 more source

Cultural differences in applying Kansei Engineering to services [PDF]

open access: yes, 2012
It is imperative for companies to provide competitive products and services at a competitive price. Products and services need to offer features and properties which can makethem distinguishable and attractive to customers.
Hartono, Markus   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The role of higher education for sustainable employment in Bangladesh

open access: yesDiscover Sustainability
Considering Bangladesh’s sustainable development, the employability of students is truly essential. However, skills development is essential for further employability, where higher educational institutions might play an extraordinary role.
Mehedi Hasan   +2 more
doaj   +1 more source

Russian-Japanese bilateral relations: limits of rapprochement [PDF]

open access: yesВосточная Азия: факты и аналитика, 2019
The article evaluates the current state of Russian-Japanese relations and analyzes the reasons why, despite the active top-level political dialogue, which particularly intensified since 2016, the two nations failed to achieve substantial progress in ...
Nelidov V.V.
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Against Anarchy and Hitler: French Nationalism and Spanish Civil War

open access: yesКонтуры глобальных трансформаций: политика, экономика, право, 2019
Combination of internal political and social crisis with armed conflict in the neighbour country behind the less dangerous frontier without any possibility of obtaining fastly any real aid from allies is one of the worst possible political scenarios in ...
V. E. Molodiakov
doaj   +1 more source

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