Results 61 to 70 of about 1,403,331 (309)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
English read by Japanese phonetic corpus: an interim report [PDF]
, 2012 The primary purpose of this paper is to explain the procedure of developing the English Read by Japanese Phonetic Corpus. A series of preliminary studies (Makino 2007, 2008, 2009) made it clear that a phonetically-transcribed computerized corpus of ...
Aoki Rika, Makino Takehiko
core +2 more sources
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
PENGGUNAAN FUKUJOSHI BAKARI DAN KURAI DALAM KALIMAT BAHASA JEPANG [PDF]
, 2015 Ningrum, Sandra Setya. “The use of FukujoshiBakariand Kuraiin Japanese Language Sentence”.Thesis.Departement of Japanese Studies Faculty of Humanities.Diponegoro University.The First Advisor Dra. Sri PujiAstuti, M. Pd. Second Advisor Elizabeth IHNR, S.S.,
Sandra, Setya Ningrum
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
A Critical Evaluation of the Translation of Japanese Literature in Korea [PDF]
Gwagyeong Ilboneo Munhak Yeongu, 2017 The translation of Japanese literature in Korea did not receive much attention during both the transitional era to the modern world and the Japanese colonial era. During this time most works of literature were simply adapted, but not translated. The anti-
Hanjung LEE
doaj +1 more source
Japanese Legacy Cohort Studies: The Hisayama Study
Journal of Epidemiology, 2018 The Hisayama Study is a population-based prospective cohort study designed to evaluate the risk factors for lifestyle-related diseases, such as stroke, coronary heart disease, hypertension, diabetes, and dementia, in a general Japanese population. The prospective follow-up surveys have been conducted in subjects aged 40 or older since 1961.
openaire +4 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source