Results 101 to 110 of about 519,644 (350)

Characterizing the Usage, Evolution and Impact of Java Annotations in Practice [PDF]

open access: green, 2020
Zhongxing Yu   +3 more
openalex   +1 more source

Annotating the Java bytecodes in support of optimization [PDF]

open access: yesConcurrency: Practice and Experience, 1997
The efficient execution of Java programs presents a challenge to hardware and software designers alike. The difficulty however lies with the Java bytecodes. Their model of a simplistic, platform-independent stack machine is well-suited for portability, though at the expense of execution speed. Various approaches are being proposed to increase the speed
Hummel, Joseph   +3 more
openaire   +2 more sources

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang   +15 more
wiley   +1 more source

PAVE: Program for assembling and viewing ESTs

open access: yesBMC Genomics, 2009
Background New sequencing technologies are rapidly emerging. Many laboratories are simultaneously working with the traditional Sanger ESTs and experimenting with ESTs generated by the 454 Life Science sequencers.
Bomhoff Matthew   +3 more
doaj   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

open access: yesAdvanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan   +21 more
wiley   +1 more source

The development and deployment of Common Data Elements for tissue banks for translational research in cancer – An emerging standard based approach for the Mesothelioma Virtual Tissue Bank

open access: yesBMC Cancer, 2008
Background Recent advances in genomics, proteomics, and the increasing demands for biomarker validation studies have catalyzed changes in the landscape of cancer research, fueling the development of tissue banks for translational research.
Farhat Ghada   +15 more
doaj   +1 more source

DepAnn - An Annotation Tool for Dependency Treebanks

open access: yes, 2005
DepAnn is an interactive annotation tool for dependency treebanks, providing both graphical and text-based annotation interfaces. The tool is aimed for semi-automatic creation of treebanks.
Kakkonen, Tuomo
core   +2 more sources

An information architecture for validating courseware [PDF]

open access: yes, 2007
Courseware validation should locate Learning Objects inconsistent with the courseware instructional design being used. In order for validation to take place it is necessary to identify the implicit and explicit information needed for validation.
Melia, Mark, Pahl, Claus
core  

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

open access: yesAdvanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li   +9 more
wiley   +1 more source

FOUNTAIN: A JAVA open-source package to assist large sequencing projects

open access: yesBMC Bioinformatics, 2001
Background Better automation, lower cost per reaction and a heightened interest in comparative genomics has led to a dramatic increase in DNA sequencing activities.
Prill Florian, Buerstedde Jean-Marie
doaj   +1 more source

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