Results 71 to 80 of about 177,962 (306)

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Diagnosis of dental problems in pet rabbits (Oryctolagus cuniculus) [PDF]

, 2008
Dental problems are very common in pet rabbits. To establish a correct diagnosis of rabbit dental pathology, a general knowledge of normal dental anatomy and physiology is necessary.
De Rycke, Lieve, Gielen, Ingrid, Hermans, Katleen, van Bree, Henri, Van Caelenberg, Annemie, Verhaert, Leen   +5 more
core   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Digital Complete Denture: Clinical Efficiency And Patient Satisfaction

International Dental Journal
Introduction: This case report demonstrates the application of a digital workflow in complete denture fabrication, highlighting its efficiency and patient acceptance compared to traditional methods.
Huang Nannan, He Yuting
doaj   +1 more source

Multimodal Optical Imaging and Modulation with Simultaneous Electrophysiology Through Smart Dura in Non‐Human Primates

Advanced Science, EarlyView.
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong, Sergio Montalvo Vargo, Gaku Hatanaka, Zhaoyu Gong, Noah Stanis, Jasmine Zhou, Tiphaine Belloir, Ruikang K. Wang, Wyeth Bair, Maysamreza Chamanzar, Azadeh Yazdan‐Shahmorad   +10 more
wiley   +1 more source

Complete Denture Rehabilitation Based On A Virtual Patient Model

International Dental Journal
Introduction: To present a digital workflow for complete denture fabrication using a virtual patient model, aimed at reducing clinical visits and improving accuracy.
Li Kai, Zhang Yan, Ai Lin, Wu Yulu
doaj   +1 more source

A Hemispherical Contact Model for Simplifying 3D Occlusal Surfaces [PDF]

, 2018
Statement of problem Currently, dental articulators can recreate mandibular movements and occlusal contacts. However, whether virtual articulators can also provide information about occluding dental surfaces, functional movements, and the mandibular ...
Carranza-Cañadas, Pilar, Castro-Garcia, Miguel, Moreno-Cabello, Pedro Ángel, Rubio-Paramio, Miguel Ángel, Thompson, Geoffrey A.   +4 more
core   +1 more source

The trouble with Roy Keane [PDF]

, 2002
This article analyses the potential legal actions that could arise out of Roy Keane's challenge on Alf-Inge Haaland in the light of the comments attributed to Keane in his recently published autobiography.
James, MD
core   +2 more sources

Luminescent Chiral Molecular Glasses by Melt‐Quenching Enantiopure BINAP

Advanced Science, EarlyView.
Melt‐quenching of enantiopure BINAP yields transparent chiral molecular glasses that retain axial chirality and display blue‐shifted luminescence together with strongly enhanced circularly polarized emission with dissymmetry factors |glum| of ≈10−2.
Nuttaporn Krittametaporn, Philipp Ralle, Dorothea Dierks, Christian Nelle, Suresh K. Vasa, Pascal Kolodzeiski, Rasmus Linser, Andreas Steffen, Sebastian Henke   +8 more
wiley   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source