Results 281 to 290 of about 129,009 (362)

Physiologically Based Pharmacokinetic Modeling in Patients With Hepatic Impairment: Are Changes in Bosutinib Exposure Profiles Driven by Altered Absorption or Distribution?

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Bosutinib is an orally available Src/Abl tyrosine kinase inhibitor and has been approved for the treatment of patients with Ph + chronic myelogenous leukemia. Bosutinib is a substrate of P‐glycoprotein (P‐gp) in vitro and is predominantly metabolized by CYP3A4 in humans with minimal urinary excretion.
Chieko Muto, Hannah M. Jones, Shinji Yamazaki   +2 more
wiley   +1 more source

Bamboo leaf flavonoids counteract lipopolysaccharide-induced gut dysfunction in aging laying hens through microbiota and metabolic reprogramming. [PDF]

Poult Sci
Shen X, Huang W, Zhan S, Lv Y, Ge C, Wu L, Lin T, Wang X, Yuan H, Yu D, Liu B.   +10 more
europepmc   +1 more source

Comparative Effects of Dietary Fat Manipulation on Fatty Acid Composition of Rat Stomach, Jejunum, and Colon Phospholipids.

, 1997
Manohar L. Garg, Robert R. Blake, Brenda REINHARD   +2 more
openalex   +2 more sources

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

Small Methods, Volume 10, Issue 2, 22 January 2026.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai, Jiawen Wang, Zihuan Lin, Danni Yu, Hui Yang, Jinsong Wei, Xiaoyu Li, Hao Hu, Chao Ni, Bing Zhao   +9 more
wiley   +1 more source

Behavioral and pharmacological effects of phytochemicals in <i>Cinnamomum verum</i> bark extract for prevention of experimental murine coccidiosis. [PDF]

Front Vet Sci
Murshed M, Alzaylaee H, Ibrahim KE, Ammari A, Ahmed H, Al-Quraishy S.   +5 more
europepmc   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

Small Methods, Volume 10, Issue 2, 22 January 2026.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz, Nima Pourafzal, Audrey T. Zhu, Zhongyuan Guo, Ronnie H. Fang, Liangfang Zhang   +5 more
wiley   +1 more source

Dietary threonine levels: effect on growth performance and gut organ measurements of indigenous Boschveld chickens. [PDF]

Trop Anim Health Prod
Sekgotodi TM, Ng'ambi JW, Mabelebele M, Manyelo TG.   +3 more
europepmc   +1 more source

Corncob‐Based Diet With Enzyme Blend Improves Body Weight, Feed Efficiency and Breast Yield of Sasso Broiler Chickens

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Supplementing a 10% corncob‐based diet with a multi‐blend enzyme improved feed efficiency, body weight and breast yield of Sasso broiler chickens without adverse effects on blood parameters, offering a cost‐effective alternative feed strategy. ABSTRACT Background Owing to the high cost of grains and protein, poultry nutritionists need to consider ...
Achiamaa Asafu‐Adjaye Koranteng, Benjamin Adjei‐Mensah, Joycelyn Okyere Darko, Richard Koblah Agbehadzi, Maxwell Ansong Okai, Gifty Ziema Bumbie, Koffi Apeti Gbogbo, Jacob Alhassan Hamidu   +7 more
wiley   +1 more source

Mitofusin 2 is required for preventing deoxynivalenol-induced porcine intestinal epithelial cell damage. [PDF]

J Anim Sci Biotechnol
Xiao K, Zhang M, Lv Q, Huang F, Xu Q, Guo J, Zhao J, Zhu H, Chen S, Liu Y.   +9 more
europepmc   +1 more source

Spontaneous arterio-enteric fistula following pancreas transplant [PDF]

, 1997
Corry, RJ, Egidi, F, Gritsch, HA, Randhawa, PS, Shapiro, R, Starzl, TE   +5 more
core