Results 61 to 70 of about 1,748,427 (276)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Endemic Babesiosis in Another Eastern State: New Jersey

Emerging Infectious Diseases, 2003
In the United States, most reported cases of babesiosis have been caused by Babesia microti and acquired in the northeast. Although three cases of babesiosis acquired in New Jersey were recently described by others, babesiosis has not been widely known ...
Barbara L. Herwaldt, Paul C. McGovern, Michal P. Gerwel, Rachael M. Easton, Rob Roy MacGregor   +4 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Producer Response to State-Sponsored Marketing Programs: The Case of Jersey Fresh [PDF]

New Jersey agricultural growers were surveyed to understand their willingness to patronize the Jersey Fresh promotional and quality grading program. Growers’ perceptions of the premium logo and their opinions of the quality grading aspect of the Jersey ...
Govindasamy, Ramu, Italia, John, Pingali, Aruna, Thatch, Daymon W.   +3 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The Comfort of Knitted Materials for Sportswear: A Focus on Air and Water Vapour Permeability

Tekstilec
Factors such as the growing popularity of sports, changing lifestyles and the increasing number of sporting events contribute significantly to the popularity of sports textiles.
Ivana Salopek Čubrić, Alenka Pavko Čuden, Goran Čubrić, Vesna Marija Potočić Matković   +3 more
doaj   +1 more source

Effect of the Calving Season and Zootechnical Parameters on Milk Yield in the Western Highlands of Cameroon

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2001
Data on 275 lactations were collected and analyzed between 1981 and 1991 in Holstein and Jersey breeds and their crosses with Gudali and White Fulani zebus in the western highlands of Cameroon. The objective of the study was to evaluate the effect of the
P. Kamga, J. N. Mbanya, N. R. Awah, Y. Mbohou, Y. Manjeli, A. Nguemdjom, B. Kamba Pamela, R. M. Njwe, P. H. Bayemi, C. Ndi, H. Imele, A. Kaméni   +11 more
doaj   +1 more source

Human Resource Management in New Jersey State Government [PDF]

, 2006
In 2005, the State of New Jersey Department of Personnel commissioned the Heldrich Center to study the critical human resource management issues confronting New Jersey state government.
Angie McGuire, Catherine L. O'Neill, Harriet A. Kass, Kathy Krepcio   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Hemoperitoneum After Cardiopulmonary Resuscitation in Peritoneal Dialysis Patients: A Tale of Two Cases

International Journal of Nephrology and Renovascular Disease, 2020
Narender Goel,1– 3 Danny B Haddad,1– 3 Deepika Jain1– 3 1New Jersey Kidney Care, Jersey City, NJ, USA; 2Division of Nephrology, CarePoint Health Hospitals, Jersey City, NJ, USA; 3Division of Nephrology, RWJ Barnabas Jersey City Medical ...
Goel N, Haddad DB, Jain D
doaj