Results 71 to 80 of about 1,748,427 (276)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Breed and season influence on milk quality parameters and in mastitis occurrence

open access: yesPesquisa Veterinária Brasileira, 2011
The aims of the present study were to evaluate the performance of Jersey and Holstein cows under different rainfall conditions (dry and rainy seasons) by monitoring aspects related to subclinical mastitis (somatic cell count, microbiological isolation ...
Diego B. Nóbrega, Hélio Langoni
doaj   +1 more source

New York - New Jersey job recovery expected to continue in 1998 [PDF]

open access: yes
The pattern of employment recovery in the New York-New Jersey region is expected to remain unbroken in 1998, despite a slight slowing of job growth.Employment - New York (State) ; Employment - New Jersey ; Federal Reserve District ...
James Orr, Mike DeMott, Rae D. Rosen
core  

Tracking America's Unsolved Homicides [PDF]

open access: yes, 2017
More than half of America's major police departments are struggling to solve homicides at the same level of success they enjoyed a decade ago, according to a study of federal crime records by the nonprofit Murder Accountability Project.The study focused ...
Eric Witzig
core  

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

CONSUMER AWARENESS OF STATE-SPONSORED MARKETING PROGRAMS: AN EVALUATION OF THE JERSEY FRESH PROGRAM [PDF]

open access: yes
The majority of consumers surveyed (77 percent) report awareness of the Jersey Fresh, state-sponsored promotional program. However, certain segments appear more likely to be familiar with Jersey Fresh and its logos than others are.
Govindasamy, Ramu   +2 more
core   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Producción y reproducción de vacas Holstein, Jersey y sus cruces en cinco localidades de Costa Rica

open access: yesCuadernos de investigación UNED, 2018
En Costa Rica el 26% del ganado vacuno está destinado a la producción de leche especializada, predominando la raza Jersey, seguida de Holstein, Guersey y Pardo Suizo.
Jose Pablo Gonzáles Blanco   +1 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

ENHANCING BUSINESS OPPORTUNITIES IN THE FOOD WHOLESALE SECTOR: A CASE STUDY OF NEW JERSEY [PDF]

open access: yes
New Jersey is very much like many other states in the northeastern region of the United States. On the other hand, it is unique in a number of ways. New Jersey is characterized by (1) a large and affluent consumer base, (2) access to major ports and air ...
Adelaja, Adesoji O.   +3 more
core   +1 more source

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