Results 181 to 190 of about 409,030 (287)

Comparative Analysis of <i>BRCA</i> Pathogenic Variant Detection in a Real-World Setting: Population Screening Versus Oncogenetic Clinics. [PDF]

JCO Precis Oncol
Armon S, Lieberman S, Michaelson-Cohen R, Tomer A, Koller-Volkow E, Levy-Lahad E, Srebnik N.   +6 more
europepmc   +1 more source

Obesity in Late Adolescence and Healthcare Costs in Young to Mid‐Adulthood

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The global prevalence of obesity has more than doubled between 1990 and 2022, making it a significant public health concern. Obesity is associated with an increased risk of various complications, including cardiovascular diseases, type 2 diabetes, as well as increased risk for all‐cause mortality.
Cheli Melzer Cohen, Gabriel Chodick, Moshe Leshno, Avi Shina, Eli Pinchevsky, Gilad Twig   +5 more
wiley   +1 more source

Effects of Dapagliflozin on Cardiovascular Outcomes in Patients With Type 2 Diabetes at Risk of Liver Fibrosis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The fibrosis‐4 (FIB‐4) score is used to identify risk of advanced liver fibrosis. This post hoc analysis investigated its prognostic value for cardiovascular (CV) outcomes and its relevance to the effects of dapagliflozin. Materials and Methods DECLARE‐TIMI 58 was a randomised, placebo‐controlled phase 3 trial investigating dapagliflozin ...
Jan Oscarsson, Monika Huhn, Yunyun Jiang, Ingrid Gause‐Nilsson, Stephen D. Wiviott, Filipe A. Moura, John P. H. Wilding, Simona Cernea, Luc Van Gaal, Avivit Cahn, Deepak L. Bhatt, Peter A. Johansson, C. David Sjöström   +12 more
wiley   +1 more source

Modeling identities among the first-sedentary communities: Emergence of clay personal ornaments in Epipaleolithic Southwest Asia. [PDF]

Sci Adv
Davin L, Sindel M, Yeshurun R, Weinstein-Evron M, Kaufman D, Shklyar B, Grosman L, Belfer-Cohen A, Khalaily H, Valla FR.   +9 more
europepmc   +1 more source

Elranatamab in Relapsed/Refractory Multiple Myeloma: Mechanisms, Clinical Evidence, and Emerging Perspectives

European Journal of Haematology, EarlyView.
ABSTRACT Relapsed and refractory multiple myeloma (RRMM) remains associated with poor outcomes, particularly in patients exposed or refractory to proteasome inhibitors, immunomodulatory agents, and anti‐CD38 monoclonal antibodies. Targeting B‐cell maturation antigen (BCMA) has emerged as an effective therapeutic strategy, prompting the development of ...
Maria Eugenia Alvaro, Enrica Antonia Martino, Santino Caserta, Mamdouh Skafi, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

The Chapters of Nehemiah [PDF]

, 2018
Willmington, Harold
core   +1 more source

Adaptive photosynthetic in drought-resistant and susceptible Jerusalem artichoke genotypes under elevated CO₂ and light intensity during drought stress. [PDF]

BMC Plant Biol
Puangbut D, Jogloy S, Songsri P, Jongrungklang N.   +3 more
europepmc   +1 more source

Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation

European Journal of Haematology, EarlyView.
ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Mamdouh Skafi, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Low serum IgE is associated with an increased risk of chronic lymphocytic leukemia: a large retrospective cohort study. [PDF]

Front Immunol
Cohen R, Elbirt D, Nemet S, Kirzhner A, Schiller T, Khadija HA, Bezalel-Rosenberg S, Asher I, Mahlab-Guri K, Wolach O, Hofstetter L.   +10 more
europepmc   +1 more source