Results 201 to 210 of about 353,631 (309)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Integrated Methylome–Transcriptome Analysis Reveals Epigenomic Remodeling and Rho GTPase–Linked Immune–Epithelial Crosstalk in Atopic Dermatitis

open access: yesAllergy, EarlyView.
Integrated methylome–transcriptome–microbiome analysis of AD skin identified thousands of DMRs. Rho GTPase signaling and actin–junctional programs emerged as central hubs integrating immune, epithelial, and microbial interactions in the pathogenesis of atopic dermatitis.
Tiina Skoog   +22 more
wiley   +1 more source

ChatGPT in urogynecology: Comparing large language model responses to human experts

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In this patient‐rated study, ChatGPT responses to common urogynecology questions were graded more highly for clarity, helpfulness, and reassurance. Findings are exploratory, and large language models should be viewed only as cautious adjuncts to expert care.
Reut Rotem   +5 more
wiley   +1 more source

Jews in the culture wars [PDF]

open access: yes, 2002
Segal, Lynne
core  

From Survival to Recovery: 25 Years of Paediatric Critical Care Transformation in Israel

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To evaluate 25‐year national trends in paediatric intensive care utilisation, patient outcomes, rehospitalisations and regional resource distribution in Israel. Methods Retrospective, population‐based cohort study of all paediatric (0–17 years) ICU hospitalisations in Israel between 1999 and 2023.
Yael Applbaum   +6 more
wiley   +1 more source

Response of Remote Tropical West Pacific Islands to Climate Variability: A Multiproxy Record From T‐Lake, Palau, Spanning the Early Holocene to Present

open access: yesArchaeometry, EarlyView.
ABSTRACT Lake sediments are natural archives of past environmental dynamics and how these systems have responded to past climate variability. Sediment geochemistry, governed by local geology and climate processes, is unique to each lake‐catchment and geochemical proxies must be validated for each study site.
Jalene Nalbant   +6 more
wiley   +1 more source

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