The innovation paradox: the role of knowledge heterogeneity in frugal innovation
Cogent Business & ManagementWith the worsening environmental crisis and the rapid advancement of Industry 4.0, more enterprises are recognizing the importance of sustainable development, yet practical challenges remain.
Jingwu Chen, Fan Zhang
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SHP2 phosphatase as a novel therapeutic target for melanoma treatment [PDF]
, 2016 Melanoma ranks among the most aggressive and deadly human cancers. Although a number of targeted therapies are available, they are effective only in a subset of patients and the emergence of drug resistance often reduces durable responses.
Bai, Yunpeng +8 more
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Discover Applied SciencesAs subsurface barriers, cutoff walls are used to reinforce embankments to prevent instability induced by reservoir seepage during water level fluctuations.
Yuchun Gao, Jingwu Zhang
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Design and Control of the Manipulator of Magnetic Surgical Forceps with Cable Transmission
MicromachinesMagnetically actuated medical robots have attracted growing research interest because magnetic force can transmit power in a non-contact manner to fix magnetic surgical instruments onto the inner wall of the abdominal cavity.
Jingwu Li, Zhijun Sun
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Prognostic implication of p27Kip1, Skp2 and Cks1 expression in renal cell carcinoma: a tissue microarray study [PDF]
, 2008 Background p27Kip1 plays a major role as a negative regulator of the cell cycle. The regulation of p27Kip1 degradation is mediated by its specific ubiquitin ligase subunits S-phase kinase protein (Skp) 2 and cyclin-dependent kinase subunit (Cks) 1 ...
Zheng Liu +4 more
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Akulturasi Unsur Kungfu Tiongkok dalam Pencak Silat Betawi [PDF]
, 2015 This study aimed to examine the influence of acculturation of Chinese Kungfu elements on Pencak Silat Betawi. The study used qualitative method and observation with interview and literature study by looking up Betawi and Pencak Silat on Batavia ...
Khosasih, A. (Andyni) +2 more
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A debris-flow monitoring devices and methods bibliography
, 2005 International audienceDebris-flow monitoring has two functions, warning and modeling. The warning function includes the following parameters: occurrence prediction and detection, proximity sensing, and discharge-estimation.
Inaba, H., Itakura, Y., Sawada, T.
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Longitudinal Bioluminescence Imaging of Primary Versus Abdominal Metastatic Tumor Growth in Orthotopic Pancreatic Tumor Models in NSG Mice [PDF]
, 2015 Objectives: The purpose of the present study was to develop and validate noninvasive bioluminescence imaging methods for differentially monitoring primary and abdominal metastatic tumor growth in mouse orthotopic models of pancreatic cancer ...
Fishel, Melissa L. +13 more
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Validation-based insertional mutagenesis (VBIM) technology identifies adenomatous polypossis coli (APC) like protein (ALP) as a novel negative regulator of NF-κB [PDF]
, 2015 Colorectal cancer (CRC) is the third leading cause of cancer related deaths in the United States. The nuclear factor κB (NF-κB) is an important family of transcription factors whose aberrant activation has been found in many types of cancer, including
Mundade, Rasika S.
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Biophysical Environmental Chemistry: A New Frontier for Chemistry
CHIMIA, 1995 The paper discusses the position and role of environmental chemistry among the other environmental disciplines. It discusses the various aspects of environmental chemistry and emphasizes the need for developing fundamental studies in biophysical
Jacques Buffle +2 more
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