Results 51 to 60 of about 137,584 (378)

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Job-shop scheduling with limited capacity buffers [PDF]

open access: yes, 2006
In this paper we investigate job-shop problems where limited capacity buffers to store jobs in non-processing periods are present. In such a problem setting, after finishing processing on a machine, a job either directly has to be processed on the ...
Brucker, Peter   +3 more
core   +3 more sources

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Job shop scheduling with beam search [PDF]

open access: yesEuropean Journal of Operational Research, 1999
Beam Search is a heuristic method for solving optimization problems. It is an adaptation of the branch and bound method in which only some nodes are evaluated in the search tree. At any level, only the promising nodes are kept for further branching and remaining nodes are pruned off permanently.
Sabuncuoglu I., Bayiz, M.
openaire   +5 more sources

Dynamic scheduling in a multi-product manufacturing system [PDF]

open access: yes, 2005
To remain competitive in global marketplace, manufacturing companies need to improve their operational practices. One of the methods to increase competitiveness in manufacturing is by implementing proper scheduling system. This is important to enable job
Hassan, Adnan   +2 more
core  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Real-Time Selection System of Dispatching Rules for the Job Shop Scheduling Problem

open access: yesMachines, 2023
Personalized market demands make the job shop scheduling problem (JSSP) increasingly complex, and the need for scheduling methods that can solve scheduling strategies quickly and easily has become very urgent.
Anran Zhao   +5 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

A Two-Phase Iterative Mathematical Programming-Based Heuristic for a Flexible Job Shop Scheduling Problem with Transportation

open access: yesApplied Sciences, 2023
In a flexible job shop problem with transportation (FJSPT), a typical flexible manufacturing system comprises transporters that pick up and deliver jobs for processing at flexible job shops.
Che Han Lim, Seung Ki Moon
doaj   +1 more source

Particle swarm optimization applied to job shop scheduling [PDF]

open access: yes, 2007
In this project we have to apply the particle swarm optimization algorithm to job shop scheduling problem. Job shop scheduling is a combinatorial optimization problem where we have to arrange the jobs which may or may not be processed in every machine in
Dwivedi , Piyush, Vishal , Vivek
core  

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