Results 111 to 120 of about 5,305,302 (256)

Beyond‐Classical Ferroelectric Metamaterials: 3D‐Printed Planar Lattices With Programmable Electro–Thermo–Mechanical Coupling

open access: yesAdvanced Science, EarlyView.
Planar ferroelectric lattices with rationally‐tailored topology and polarization achieve programmable piezoelectric and pyroelectric properties. Analytical modeling, homogenization, and experiments collectively demonstrate enhanced and tunable longitudinal, transverse, and shear piezoelectric responses, together with substantially improved ...
Jiahao Shi   +6 more
wiley   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

open access: yesAdvanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong   +15 more
wiley   +1 more source

The tragic spectacle of "Krusty" John, "Sideshow" Pete and little Tony Abbart, with apologies to groening, 1 September 2004 [picture] /

open access: yes, 2004
Title from inscriptions.; Inscriptions: "The tragic spectacle of "Krusty" John, "Sideshow" Peter and little Tony Abbart"--In ink above drawing; "With apologies to groening"--In ink lower right; "01-09-04"--In pencil on verso; "Spooner"--Signed in ink ...
Spooner, John, 1946-
core  

PBRM1 Deficiency in Microglia Leads to Excessive Neurogenesis and Autism‐Like Behaviors via the CCL5‐CCR1/5‐β‐catenin Signaling Axis

open access: yesAdvanced Science, EarlyView.
Microglial PBRM1 deficiency drives excessive hippocampal neurogenesis by enhancing CCL5–CCR1/5 signaling, leading to autism‐like behaviors. A pro‐inflammatory IL1α+/TNFα+ microglial subset is identified as a key cellular contributor to this process. PBRM1 represses Ccl5 expression at the transcriptional level.
Yang‐Yang Duan   +12 more
wiley   +1 more source

Checkpoint‐Directed Glycoengineering Reprograms the Vascular Lumen for Siglec‐Mediated Immune Regulation

open access: yesAdvanced Science, EarlyView.
Checkpoint‐directed glycoengineering installs sialylated ligands on the donor vascular lumen during ex vivo preservation, creating a localized Siglec‐7/9‐engaging interface. The engineered glycocalyx suppresses immune‐cell activation, complement deposition, and microvascular injury in arterial and kidney allografts while preserving endothelial ...
Md Mohosin Rana   +19 more
wiley   +1 more source

General Correspondence; Young, John Wesley, 1888

open access: yes, 1888
Three letters from John Wesley Young (son of John Willard and Elizabeth Canfield Young) to John M.
Young, John Wesley, 1868-1928
core  

John Black's portrait unveiled [PDF]

open access: yesThe Bulletin of the Royal College of Surgeons of England, 2011
openaire   +1 more source

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