Results 41 to 50 of about 5,307,648 (153)

Common genetic variants and modification of penetrance of BRCA2-associated breast cancer.

PLoS Genetics, 2010
The considerable uncertainty regarding cancer risks associated with inherited mutations of BRCA2 is due to unknown factors. To investigate whether common genetic variants modify penetrance for BRCA2 mutation carriers, we undertook a two-staged genome ...
Mia M Gaudet, Tomas Kirchhoff, Todd Green, Joseph Vijai, Joshua M Korn, Candace Guiducci, Ayellet V Segrè, Kate McGee, Lesley McGuffog, Christiana Kartsonaki, Jonathan Morrison, Sue Healey, Olga M Sinilnikova, Dominique Stoppa-Lyonnet, Sylvie Mazoyer, Marion Gauthier-Villars, Hagay Sobol, Michel Longy, Marc Frenay, GEMO Study Collaborators, Frans B L Hogervorst, Matti A Rookus, J Margriet Collée, Nicoline Hoogerbrugge, Kees E P van Roozendaal, HEBON Study Collaborators, Marion Piedmonte, Wendy Rubinstein, Stacy Nerenstone, Linda Van Le, Stephanie V Blank, Trinidad Caldés, Miguel de la Hoya, Heli Nevanlinna, Kristiina Aittomäki, Conxi Lazaro, Ignacio Blanco, Adalgeir Arason, Oskar T Johannsson, Rosa B Barkardottir, Peter Devilee, Olofunmilayo I Olopade, Susan L Neuhausen, Xianshu Wang, Zachary S Fredericksen, Paolo Peterlongo, Siranoush Manoukian, Monica Barile, Alessandra Viel, Paolo Radice, Catherine M Phelan, Steven Narod, Gad Rennert, Flavio Lejbkowicz, Anath Flugelman, Irene L Andrulis, Gord Glendon, Hilmi Ozcelik, OCGN, Amanda E Toland, Marco Montagna, Emma D'Andrea, Eitan Friedman, Yael Laitman, Ake Borg, Mary Beattie, Susan J Ramus, Susan M Domchek, Katherine L Nathanson, Tim Rebbeck, Amanda B Spurdle, Xiaoqing Chen, Helene Holland, kConFab, Esther M John, John L Hopper, Saundra S Buys, Mary B Daly, Melissa C Southey, Mary Beth Terry, Nadine Tung, Thomas V Overeem Hansen, Finn C Nielsen, Mark H Greene, Phuong L Mai, Ana Osorio, Mercedes Durán, Raquel Andres, Javier Benítez, Jeffrey N Weitzel, Judy Garber, Ute Hamann, EMBRACE, Susan Peock, Margaret Cook, Clare Oliver, Debra Frost, Radka Platte, D Gareth Evans, Fiona Lalloo, Ros Eeles, Louise Izatt, Lisa Walker, Jacqueline Eason, Julian Barwell, Andrew K Godwin, Rita K Schmutzler, Barbara Wappenschmidt, Stefanie Engert, Norbert Arnold, Dorothea Gadzicki, Michael Dean, Bert Gold, Robert J Klein, Fergus J Couch, Georgia Chenevix-Trench, Douglas F Easton, Mark J Daly, Antonis C Antoniou, David M Altshuler, Kenneth Offit   +120 more
doaj   +1 more source

Maternal Exposure to Medications and the Risk of Congenital and Early‐Onset Hearing Loss in Children: A Systematic Review and a Meta‐Analysis

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 3, September 2025.
ABSTRACT Background Congenital hearing loss (CHL) affects approximately 1–2 in 1000 children and significantly impacts development. Exposure to medications during pregnancy may impact offspring hearing; however, the ototoxic effects of different drugs have not been systematically investigated.
Asli Sena Kücükyildiz, Mette Østergaard Thunbo, Christer Zøylner Swan, David P. Burgner, Jessica E. Miller, Therese Ovesen, Lars Henning Pedersen   +6 more
wiley   +1 more source

“Published but not printed”: John Toland and the circulation of manuscripts c.1700-1722. [PDF]

, 1998
The radical writer John Toland had a number of his works printed but not published, instead distributing them individually to members of his circle of sympathisers and patrons. By this means he avoided official censorship. The range of his contacts shows
Champion, Justin
core   +3 more sources

The Magistracy of Moses: The Old Testament in Local Government, 1689–1750

Journal for Eighteenth-Century Studies, Volume 48, Issue 2, Page 199-215, June 2025.
Abstract This article explores the popularity of Moses as a model for government in the early eighteenth century. It examines references to Moses in sermons preached at civic or political events such as assizes, elections of mayors, and meetings of reform societies.
Daniel Rignall
wiley   +1 more source

The Enlightenment prophet: Muhammad in early modern Europe

Journal of the British Academy
This article examines the place of Islam in the intellectual history of the European Enlightenment. In 1649, the English civil war resulted in the establishment of the Commonwealth under Oliver Cromwell and the execution of King Charles I;
John Tolan
doaj   +1 more source

From Voltaire's Quakers to John Boyle's Methodists: Religious Dispute, Bardolatry, and ‘Patriot Enthusiasm’

Journal for Eighteenth-Century Studies, Volume 47, Issue 4, Page 345-363, December 2024.
Abstract Through the prism of Voltaire's letters on the Quakers (1733) and John Boyle's riposte in his preface to Father Brumoy's The Greek Theatre (1759), some Shakespeare criticism of the period is shown to have drawn on issues of religious controversy, in this case, Methodist enthusiasm, to formulate some of the principal tenets of fledgling ...
Jonathan P.A. Sell
wiley   +1 more source

Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.

PLoS Medicine, 2016
BackgroundObservational epidemiological studies have shown that high body mass index (BMI) is associated with a reduced risk of breast cancer in premenopausal women but an increased risk in postmenopausal women.
Yan Guo, Shaneda Warren Andersen, Xiao-Ou Shu, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Montserrat Garcia-Closas, Roger L Milne, Marjanka K Schmidt, Jenny Chang-Claude, Allison Dunning, Stig E Bojesen, Habibul Ahsan, Kristiina Aittomäki, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, Natalia V Bogdanova, Bernardo Bonanni, Anne-Lise Børresen-Dale, Judith Brand, Hiltrud Brauch, Hermann Brenner, Thomas Brüning, Barbara Burwinkel, Graham Casey, Georgia Chenevix-Trench, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Peter Devilee, Thilo Dörk, Martine Dumont, Peter A Fasching, Jonine Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Henrik Flyger, Florentia Fostira, Marilie Gammon, Graham G Giles, Pascal Guénel, Christopher A Haiman, Ute Hamann, Maartje J Hooning, John L Hopper, Anna Jakubowska, Farzana Jasmine, Mark Jenkins, Esther M John, Nichola Johnson, Michael E Jones, Maria Kabisch, Muhammad Kibriya, Julia A Knight, Linetta B Koppert, Veli-Matti Kosma, Vessela Kristensen, Loic Le Marchand, Eunjung Lee, Jingmei Li, Annika Lindblom, Robert Luben, Jan Lubinski, Kathi E Malone, Arto Mannermaa, Sara Margolin, Frederik Marme, Catriona McLean, Hanne Meijers-Heijboer, Alfons Meindl, Susan L Neuhausen, Heli Nevanlinna, Patrick Neven, Janet E Olson, Jose I A Perez, Barbara Perkins, Paolo Peterlongo, Kelly-Anne Phillips, Katri Pylkäs, Anja Rudolph, Regina Santella, Elinor J Sawyer, Rita K Schmutzler, Caroline Seynaeve, Mitul Shah, Martha J Shrubsole, Melissa C Southey, Anthony J Swerdlow, Amanda E Toland, Ian Tomlinson, Diana Torres, Thérèse Truong, Giske Ursin, Rob B Van Der Luijt, Senno Verhoef, Alice S Whittemore, Robert Winqvist, Hui Zhao, Shilin Zhao, Per Hall, Jacques Simard, Peter Kraft, Paul Pharoah, David Hunter, Douglas F Easton, Wei Zheng   +110 more
doaj   +1 more source

An Integrative Review of Strength Milestoning in Mid-Stage Achilles Tendon Rehab

Biomechanics
Current rehabilitation protocols for transitioning patients to late-stage recovery, evaluating return-to-play (RTP) clearance, and assessing tendon characteristics exhibit significant heterogeneity.
Chris Toland, John Cronin, Duncan Reid, Mitzi S. Laughlin, Jeremy L. Fleeks   +4 more
doaj   +1 more source

Revalidation of Teachers' Sense of Efficacy Scale using Ghanaian in‐service teachers: Multidimensional item response theory with factor analyses

Psychology in the Schools, Volume 61, Issue 5, Page 1789-1807, May 2024.
Abstract Teachers' Sense of Efficacy Scale (TSES), since its development, has gained much popularity because of its adequate psychometric properties. Yet, scholarly information on the soundness of this instrument in the African context has not been documented.
Frank Quansah, Edmond K. Agormedah, Francis Ankomah, Medina Srem‐Sai, Regina M. Nugba, John E. Hagan Jr., Thomas Schack   +6 more
wiley   +1 more source

Philosophy's past: Cognitive values and the history of philosophy

Philosophy and Phenomenological Research, Volume 108, Issue 3, Page 585-606, May 2024.
Abstract Recent authors hold that the role of historical scholarship within contemporary philosophical practice is to question current assumptions, to expose vestiges or to calibrate intuitions. On these views, historical scholarship is dispensable, since these roles can be achieved by nonhistorical methods.
Phil Corkum
wiley   +1 more source