Results 111 to 120 of about 1,446,234 (287)

Net profitability of airline alliances, an empirical study [PDF]

, 2010
This study examines the net return for airlines before and after joining an alliance. The research database was compiled from ICAOData, and comprised 15 international airlines as subjects and their net financial results for a period of 11 years as ...
Lin, Bo, Pérezgonzález, Jose D.
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Effect of Rotational Speed on Mechanical Properties of AA5083/AA6082 Friction Stir Welded T-Joints for Naval Applications

Metals
This study evaluates the influence of rotational speed on the mechanical and microstructural properties of T-joints fabricated via friction stir welding (FSW) using dissimilar aluminum alloys, AA5083 and AA6082, for naval applications.
Guido Di Bella, Chiara Borsellino, Mohamed Chairi, Davide Campanella, Gianluca Buffa   +4 more
doaj   +1 more source

Joining the dots through Scottish crofting education [PDF]

, 2017
The ‘Crofting Connections’ (Ceanglaichean Croitearachd) project is described in this article as an exemplar of the prescribed ‘Scottish approach’ to Education for Sustainable Development (ESD).
Blee, Harry, Britton, Alan, Hunt, Rachel
core  

Simultaneous precise editing of multiple genes in human cells

, 2019
. When double-strand breaks are introduced in a genome by CRISPR they are repaired either by non-homologous end joining (NHEJ), which often results ...
Chintalapati, M., Kanis, P., Macak, D., Maricic, T., Pääbo, S., Riesenberg, S.   +5 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Introduction of Functional Elements with Double-Sided Self-Pierce Riveting

Journal of Manufacturing and Materials Processing
The introduction of functional elements is essential for many industrial components which rely on elements such as bolts, screws, nuts, or clips that are integrated into the workpieces.
Rafael M. Afonso, Luís M. Alves
doaj   +1 more source

Tool and process for miniature explosive joining of tubes [PDF]

, 1987
A tool and process to be used in the explosive joining of tubes is disclosed. The tool consists of an initiator, a tool form, and a ribbon explosive.
Bailey, James W., Bement, Laurence J.
core   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Walter Burley Griffin and Marion Mahony Griffin, Architects of Anthroposophy [PDF]

, 2012
This paper reveals that the first public lecture in Australia on biodynamic agriculture was held on 26 June 1938 at the home of the architects Walter Burley Griffin and Marion Mahoney Griffin at Castlecrag, Sydney.
Paull, John
core