Results 151 to 160 of about 1,446,234 (287)
Review of beryllium technology for spacecraft applications [PDF]
Joining, working, and structural properties of beryllium and beryllium alloys for spacecraft ...
Moss, R. G.
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
BioResourcesThe joint strength that develops in ultrasonic bonding of fiber-based materials is governed by multiple macro- and microscopic structural parameters whose interactions complicate the isolation of individual effects.
Nema Aldarwich +3 more
doaj
Beyond Short Microhomologies: Mismatch-Compatible Pol θ-Mediated DNA Damage Repair. [PDF]
BioessaysLi Y, Wood RD.
europepmc +1 more source
Low-temperature solder for joining large cryogenic structures [PDF]
Three joining methods were considered for use in fabricating cooling coils for the National Transonic Facility. After analysis and preliminary testing, soldering was chosen as the cooling coil joining technique over mechanical force fit and brazing ...
Buckley, J. D., Sandefur, P. G., Jr.
core +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +8 more
wiley +1 more source
Caffeine inhibits nonhomologous end joining by impairing ligase IV/XRCC4 function. [PDF]
Nucleic Acids ResKumari S +4 more
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai +12 more
wiley +1 more source