Results 31 to 40 of about 327,730 (260)

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Implicit Coordination: Acting Quasi-Jointly on Implicit Shared Intentions

Journal of Social Ontology, 2019
We identify a social phenomenon in which large numbers of people seem to work towards a shared goal without explicitly trying to do so. We argue that this phenomenon – implicit coordination – is best understood as a form of joint agency differing from ...
Martens Judith, Roelofs Luke
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A monthly sub-national Harmonized Food Insecurity Dataset for comprehensive analysis and predictive modeling

Scientific Data
Food insecurity is a complex, multidimensional concept challenging to measure comprehensively. Effective anticipation, monitoring, and mitigation of food crises require timely and comprehensive global data.
Melissande Machefer, Michele Ronco, Anne-Claire Thomas, Michael Assouline, Melanie Rabier, Christina Corbane, Felix Rembold   +6 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

From Joint Activity to the Construction of New SocialCommunities: Jointness. Creativity. Education. School (Roundtable of the methodological seminar supervisedby V.V. Rubtsov and B.D. Elkonin)

Культурно-историческая психология, 2018
On July 10, 2018 a discussion seminar “From Joint Activity to the Construction of New Social Communities: Jointness. Creativity. Education. School” was held at the Moscow State University of Psychology and Education dedicated to the 70th birthday of ...
Rubtsov V.V.,, Lektorsky V.A.,, Asmolov A.G., Kudryavcev V.T.,, Froumin I.D.,, Gromyko Y.V.,, Elkonin B.D., , Lazarev V.S., Bolotov V.A.,, Kravtsov G.G.,, Kravtsova E.E.,, Zuckerman G.A.,, Urazalieva G.K.,   +12 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

ON AGENCY AND JOINT ACTION

Studia Universitatis Babeș-Bolyai. Philosophia, 2020
In this article I focus on two conflicting directions of supraindividualism concerning joint agency. The two representative authors here are Schmitt (2003b) and Pettit (2003).
Andreea POPESCU
doaj   +1 more source