Results 61 to 70 of about 2,199,879 (290)

Comments on Joint Terms in Gravitational Action

, 2017
This paper compares three different methods about computing joint terms in on-shell action of gravity, which are identifying the joint term by the variational principle in Dirichlet boundary condition, treating the joint term as the limit contribution of
Ruan, Shan-Ming, Yang, Run-Qiu
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Analyzing gaze and hand movement patterns in leader-follower interactions during a time-continuous cooperative manipulation task

Frontiers in Psychology
In daily life, people often interact by taking on leader and follower roles. Unlike laboratory experiments, these interactions unfold naturally and continuously.
Minghao Cheng, Anoushiravan Zahedi, Anoushiravan Zahedi, Ricarda I. Schubotz, Ricarda I. Schubotz, Florentin Wörgötter, Minija Tamosiunaite, Minija Tamosiunaite   +7 more
doaj   +1 more source

The Joint Action Effect on Memory as a Social Phenomenon: The Role of Cued Attention and Psychological Distance

Frontiers in Psychology, 2017
In contrast to individual tasks, a specific social setting is created when two partners work together on a task. How does such a social setting affect memory for task-related information?
Ullrich Wagner, Anna Giesen, Judith Knausenberger, Gerald Echterhoff   +3 more
doaj   +1 more source

Extending Feynman's Formalisms for Modelling Human Joint Action Coordination

, 2009
The recently developed Life-Space-Foam approach to goal-directed human action deals with individual actor dynamics. This paper applies the model to characterize the dynamics of co-action by two or more actors. This dynamics is modelled by: (i) a two-term
Bernstein N. A., Bernstein N. A., EUGENE V. AIDMAN, Fogassi L., Hebb D. O., Ivancevic V., LEONG YEN, Lewin K., Sutton R. S., VLADIMIR G. IVANCEVIC   +9 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Joint action and development [PDF]

Given the premise that joint action plays some role in explaining how humans come to understand minds, what could joint action be? Not what a leading account, Michael Bratman’s, says it is. For on that account engaging in joint action involves sharing
Butterfill, Stephen A. (Stephen Andrew)
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Collective Emotions and Joint Action

Journal of Social Ontology, 2016
In contemporary philosophy of collective intentionality, emotions, feelings, moods, and sentiments do not figure prominently in debates on the explanation and justification of joint action.
Mikko Salmela, Michiru Nagatsu
doaj   +2 more sources