Results 41 to 50 of about 2,439,370 (299)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

СОВМЕСТНАЯ ДЕЯТЕЛЬНОСТЬ И ОТКРЫТАЯ ПРОФЕССИОНАЛИЗАЦИЯ ПЕДАГОГА КАК КОНЦЕПТУАЛЬНЫЕ ОСНОВЫ НАСТАВНИЧЕСТВА

open access: yesНаучно-педагогическое обозрение, 2019
Анализируется проблема организации наставничества как механизм реализации непрерывного образования взрослых, как механизм внутрифирменного обучения работников, позволяющий закрепить и адаптировать их в профессии.
Поздеева Светлана Ивановна
doaj   +1 more source

Physical Activity Minimum Threshold Predicting Improved Function in Adults With Lower‐Extremity Symptoms [PDF]

open access: yes, 2017
Objective To identify an evidence‐based minimum physical activity threshold to predict improved or sustained high function for adults with lower‐extremity joint symptoms.
Ainsworth, Barbara   +9 more
core   +1 more source

Fluorescence optical imaging for treatment monitoring in patients with early and active rheumatoid arthritis in a 1-year follow-up period [PDF]

open access: yes, 2019
BACKGROUND: Fluorescence optical imaging (FOI) enables visualization of inflammation in the hands in rheumatic joint diseases with currently a lack of long-term follow-up studies.
Backhaus, Marina   +10 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

ПОНИМАНИЕ КАК ЕДИНИЦА СОДЕРЖАНИЯ ОБРАЗОВАНИЯ

open access: yesНаучно-педагогическое обозрение, 2017
Рассматривается образовательное содержание акта понимания в контексте педагогики Совместной деятельности. Выделяются функции этого действия: смыслопорождение, познавательная функция и психологическая функция.
Колпаков Сергей Николаевич
doaj   +1 more source

Concession as the form of implementation of public-private partnership projects: the general description of accounting object

open access: yesВісник Житомирського державного технологічного університету: Серія: економіка, управління та адміністрування, 2019
The article explores the reasons for the emergence of the need for public-private partnership. The study found out that the most important reason was the existence of a gap between the public tasks that were set and the resources available in the state ...
V.V. Kovalchuk
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Thinking, Feeling, and Moving in Kindergarten Children: How Motor Competence Shapes Executive Function Skills and Emotion Comprehension in Girls

open access: yesChildren
Background/Objectives: Increased screen time partially replaces social interaction, physical activity, and outdoor play in kindergarten children, leading to a risk of decreased cognitive, emotional, and motor skills.
Elena A. Chichinina   +3 more
doaj   +1 more source

The role of proteases in pathologies of the synovial joint [PDF]

open access: yes, 2008
Synovial (diarthrodial) joints are employed within the body to provide skeletal mobility and have a characteristic structure adapted to provide a smooth almost frictionless surface for articulation.
Buttle, D, Jones, GC, Riley, GP
core   +1 more source

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