Results 51 to 60 of about 2,439,370 (299)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Towards the integration and development of a cross-European research network and infrastructure:the DEterminants of DIet and Physical ACtivity (DEDIPAC) Knowledge Hub [PDF]

open access: yes, 2014
To address major societal challenges and enhance cooperation in research across Europe, the European Commission has initiated and facilitated ‘joint programming’.
Ahrens, Wolfgang   +35 more
core   +12 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

СТРУКТУРА И ДИНАМИКА ФОРМИРОВАНИЯ ДЕЙСТВИЙ ПО ОБРАЗОВАТЕЛЬНОМУ ПРОЕКТИРОВАНИЮ В ШКОЛЕ СОВМЕСТНОЙ ДЕЯТЕЛЬНОСТИ

open access: yesНаучно-педагогическое обозрение, 2017
Рассматриваются особенности формирования универсальных учебных действий в МБОУ СОШ № 49 г. Томска (школа совместной деятельности). Данные особенности представлены системой обучения учащихся действиям по совместному проектированию своего образования ...
Соколов Виктор Юрьевич
doaj   +1 more source

Integration of geochemical and geophysical data at a NAPL-contaminated site [PDF]

open access: yes, 2012
The joint use of borehole geo-electrical measurements and the chemico-physical monitoring of the subsoi is discussed; it permitted in the specific case to locate the zone characterized by intense bio-degradation activity, demonstrating the effectiveness ...
, A., Godio, Alberto, Weher, M.
core  

Deep Multimodal Representation Learning from Temporal Data

open access: yes, 2017
In recent years, Deep Learning has been successfully applied to multimodal learning problems, with the aim of learning useful joint representations in data fusion applications.
Bernal, Edgar A.   +5 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

BARRIERS OF STRATEGIC ALLIANCES ORGANIZATION

open access: yesСтатистика и экономика, 2016
General barriers of organization of different types of strategic alliances have beenconsidered in the article. There are several recommendations for overcoming themin cases of international alliances, and in case of work in one state.
Vladislav M. Sannikov
doaj   +1 more source

The NHS-HE Forum [PDF]

open access: yes, 2006
This paper discusses the formation of the NHS-HE Forum by Professor Roland Rosner in 2001. It looks at the aims and objectives of the Forum and maps current progress. The second part of the paper looks particularly at the NHS-HE Procurement Group and the
Ayris, P, Teague, M
core  

Joint segmentation of multivariate time series with hidden process regression for human activity recognition

open access: yes, 2013
The problem of human activity recognition is central for understanding and predicting the human behavior, in particular in a prospective of assistive services to humans, such as health monitoring, well being, security, etc.
Amirat, Yacine   +4 more
core   +4 more sources

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