Results 81 to 90 of about 2,439,370 (299)

Sociogenesis of Joint Action: Mutual Understanding between Individuals as a Precondition for Understanding Things. Interview (Carried out by V.T. Kudryavtsev)

Культурно-историческая психология, 2018
This interview with V.V. Rubtsov, Rector of MSUPE, full member of the Russian Academy of Education, marks the opening of a new university project, “Psychology and Me. The Living Stories” (created and implemented by V.T. Kudryavtsev).
Rubtsov V.V.,
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Quasar Luminosity Functions from Joint Evolution of Black Holes and Host Galaxies

, 2006
We show that our previously proposed anti-hierarchical baryon collapse scenario for the joint evolution of black holes and host galaxies predicts quasar luminosity functions at redshifts 1 ...
A. Lapi, Bower R. G., F. Shankar, G. De Zotti, G. L. Granato, Giacconi R., Granato G. L., Haehnelt M. G., J. Mao, Kitayama T., Kodama T., Kormendy J., L. Danese, L. Silva, Lacey C., Mathez G., Sasaki S., Small T. A., Soltan A., Srianand R.   +19 more
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

A NASA/RAE cooperation in the development of a real-time knowledge-based autopilot [PDF]

As part of a US/UK cooperative aeronautical research program, a joint activity between the NASA Dryden Flight Research Facility and the Royal Aerospace Establishment on knowledge-based systems was established.
Belle, Steven D., Brumbaugh, Randal W., Butler, Geoff, Corbin, Malcolm, Daysh, Colin, Duke, Eugene L.   +5 more
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Planned Joint International Activities

Marine Research Infrastructures and observing systems or networks play an important role in improving the understanding of the Ocean's functioning by delivering fit-for-purpose observational data, providing access to observation and experimentation tools, and providing services to a broad range of users.
Lips, Inga, Pearlman, Jay, Brix, Holger, Delauney, Laurent   +3 more
openaire   +4 more sources

“There Was No Green Tick”: Discovering the Functions of a Widget in a Joint Problem-Solving Activity and the Consequences for the Participants’ Discovering Process

Multimodal Technologies and Interaction, 2018
In recent years, tangible user interfaces (TUI) have gained in popularity in educational contexts, among others to implement problem-solving and discovery learning science activities.
Patrick Sunnen, Béatrice Arend, Valérie Maquil   +2 more
doaj   +1 more source