Results 101 to 110 of about 12,189,357 (395)
Use of the Metropolis-Hastings Algorithm in the Calibration of a Patient Level Simulation of Prostate Cancer Screening [PDF]
Designing cancer screening programmes requires an understanding of epidemiology, disease natural history and screening test characteristics. Many of these aspects of the decision problem are unobservable and data can only tell us about their joint ...
Chilcott, Jim+2 more
core
Skeletal immaturity, rostral sparing, and disparate hip morphologies as biomechanical causes for Legg-Calvé-Perthes’ disease [PDF]
Legg-Calvé-Perthes' (Perthes') disease is a developmental disease of the hip joint that may result in numerous short and long term problems. The etiology of the disease remains largely unknown, but the mechanism is believed to be vascular and/or ...
Acheson+191 more
core +1 more source
ABSTRACT Dopaminergic medication and deep brain stimulation (DBS) improve motor symptoms in Parkinson's disease (PD), but levodopa response alone may not predict DBS outcomes. We retrospectively analyzed 19 PD patients undergoing levodopa challenges with and without prior transcranial direct current stimulation targeting a defined PD response network ...
Lukas L. Goede+3 more
wiley +1 more source
Recent updates for biomaterials used in total hip arthroplasty
Background Total hip arthroplasty (THA) is probably one of the most successful surgical interventions performed in medicine. Through the revolution of hip arthroplasty by principles of low friction arthroplasty was introduced by Sir John Charnley in ...
Chang Yong Hu, Taek-Rim Yoon
doaj +1 more source
Association of circulating levels of MMP-8 with mortality from respiratory disease in patients with rheumatoid arthritis. [PDF]
Matrix metalloproteinases (MMPs) are implicated in the destruction of the joint and have been shown to be strongly associated with inflammation in rheumatoid arthritis (RA).
Dawes, PT, Mattey, DL, Nixon, NB
core +1 more source
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte+13 more
wiley +1 more source
Peri-articular histiocytic sarcoma and previous joint disease in Bernese Mountain Dogs.
BACKGROUND Peri-articular histiocytic sarcoma (PAHS) occurs in dogs, including Bernese Mountain Dogs (BMD). An etiologic relationship with previous joint disease has not been documented. HYPOTHESIS Peri-articular histiocytic sarcoma in BMD will be more
L. B. Kuijk+8 more
semanticscholar +1 more source
Nonlinear association structures in flexible Bayesian additive joint models
Joint models of longitudinal and survival data have become an important tool for modeling associations between longitudinal biomarkers and event processes.
Greven, Sonja+2 more
core +1 more source
Joint disease mapping using six cancers in the Yorkshire region of England [PDF]
OBJECTIVES: The aims of this study were to model jointly the incidence rates of six smoking related cancers in the Yorkshire region of England, to explore the patterns of spatial correlation amongst them, and to estimate the relative weight of smoking ...
Downing, A.+4 more
core +3 more sources
Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng+7 more
wiley +1 more source