Results 141 to 150 of about 12,189,357 (395)

YTHDF3 regulates IL32 mRNA stability to promote osteogenic differentiation of bone mesenchymal stem cells in ankylosing spondylitis

open access: yesJournal of Translational Medicine
Background As a member of the family of the YTH domain and a an m6A reader, YTHDF3 is implicated in cancer and inflammatory diseases. However, its function in ankylosing spondylitis (AS)—a chronic inflammatory disease marked by aberrant bone formation—is
Bole Zhou   +6 more
doaj   +1 more source

Relationship of orthopedic examination, goniometric measurements, and radiographic signs of degenerative joint disease in cats

open access: yesBMC Veterinary Research, 2012
BackgroundAvailable information suggests a mismatch between radiographic and orthopedic examination findings in cats with DJD. However, the extent of the discrepancy between clinical and radiographic signs of OA in companion animals has not been ...
Duncan B X Lascelles   +5 more
semanticscholar   +1 more source

Two‐Year Follow‐Up of a Multidisciplinary Lifestyle Intervention for Rheumatoid Arthritis and Osteoarthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective The Plants for Joints intervention (PFJ), including a whole‐food plant‐based diet, exercise, and stress reduction, reduced signs and symptoms of rheumatoid arthritis (RA) or metabolic syndrome‐associated hip or knee osteoarthritis (MSOA) compared to usual care. This study examined outcomes two years later. Methods After two 16‐week randomized
Carlijn A. Wagenaar   +10 more
wiley   +1 more source

Gastrointestinal Perforation as a Safety Concern Among Patients With Rheumatoid Arthritis Receiving JAK Inhibitor Therapy: A Systematic Review and Network Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri   +7 more
wiley   +1 more source

Atrophy in Joint Disease [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1891
n ...
openaire   +3 more sources

Moderators and mediators of pain and function outcomes in a new service delivery model for management of knee osteoarthritis in primary care (PARTNER): Secondary exploratory analysis of a randomized controlled trial

open access: yesArthritis Care &Research, Accepted Article.
Objective Explore moderators and mediators influenced changes in pain and function in people with knee osteoarthritis (OA) receiving a new model of primary care service delivery (PARTNER), at 12 months (ACTRN12617001595303). Methods Secondary analyses of a cluster randomized controlled trial comparing PARTNER to usual general practitioner‐delivered ...
Abdolhay Farivar   +12 more
wiley   +1 more source

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

open access: yesACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi   +11 more
wiley   +1 more source

Understanding the Twentieth Century Decline in Chronic Conditions Among Older Men [PDF]

open access: yes
I use a sample of Union Army veterans to trace the impact of a high infant mortality rate in area of enlistment, such infectious disease as acute respiratory infections, measles, typhoid fever, tuberculosis, rheumatic fever, diarrhea, and malaria while ...
Dora L. Costa
core  

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