Results 21 to 30 of about 1,787,266 (342)

The potential for dietary factors to prevent or treat osteoarthritis [PDF]

, 2014
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping, Cassidy, Aedín, Clark, Ian M., Davidson, Rose K., Donell, Simon T., Green, Jonathan A., Hirst-Jones, Kimberley L., Jupp, Orla, Macgregor, Alexander J.   +8 more
core   +1 more source

CX3CL1 promotes M1 macrophage polarization and osteoclast differentiation through NF-κB signaling pathway in ankylosing spondylitis in vitro

Journal of Translational Medicine, 2023
Background Ankylosing spondylitis (AS) is an autoimmune disease with a genetic correlation and is characterized by inflammation in the axial skeleton and sacroiliac joints.
Xinzhe Feng, Shanbang Zhu, Junjie Qiao, Zhou Ji, Bole Zhou, Weidong Xu   +5 more
doaj   +1 more source

New insights into the impact of neuro-inflammation in rheumatoid arthritis. [PDF]

, 2014
Rheumatoid arthritis (RA) is considered to be, in many respects, an archetypal autoimmune disease that causes activation of pro-inflammatory pathways resulting in joint and systemic inflammation.
Akasbi, Alten, Askling, Axford, Barrick, Bean, Bekkelund, Bongartz, Burmester, Burmester, Capellino, Cheng, Chiu, Chou, Combs, De Almeida, De Rycke, Detrait, Diamond, Doran, Doran, Emmer, Fayed, Feldmann, Firestein, Franklyn A. Howe, Germano, Gregersen, Gussew, Hamed, Harris, Ho, Hull, Hunter, Inan, Jacobs, Kaltsonoudis, Keane, Keystone, King, Klareskog, Lauvsnes, Lee, Leombruno, Lipsky, Listing, MacGregor, Mahdi, Malaviya, Markenson, McInnes, Medeiros, Mellor, Meseguer, Mikuls, Morris, Nadeau, Ni Mhuircheartaigh, Nicholas R. Fuggle, Nidhi Sofat, Nishioku, Norheim, O'Callaghan, Ogawa, Panayi, Parks, Rachel L. Allen, Ramiro, Rech, Rosenblum, Salliot, Salmon-Ceron, Scher, Schoels, Schweinhardt, Scott, Senaldi, Serrats, Skelly, Smolen, Sokka, Steens, Strangfeld, Symmons, Taylor, Teeling, Thomson, Tracey, Tubach, Upadhyay, van der Woude, van Heemst, van Vollenhoven, Vincent, Wallis, Wartolowska, Wegner, Wellcome Trust Case Control Consortium., Wendler, Weyand, Wolfe, Woolf, Zivadinov   +102 more
core   +2 more sources

The Effect of Autologous Protein Solution on the Inflammatory Cascade in Stimulated Equine Chondrocytes

Frontiers in Veterinary Science, 2019
Cartilage injury occurs commonly in equine athletes, often precipitating posttraumatic osteoarthritis (PTOA). Orthobiologics such as autologous conditioned serum (ACS) and autologous protein solution (APS) may be useful in decreasing posttraumatic ...
Renata L. Linardi, Michael E. Dodson, Kaitlyn L. Moss, William J. King, Kyla F. Ortved   +4 more
doaj   +1 more source

Characterization of host factors associated with the internal ribosomal entry sites of foot-and-mouth disease and classical swine fever viruses

Scientific Reports, 2022
Foot-and-mouth disease virus (FMDV) and classical swine fever virus (CSFV) possess positive-sense single-stranded RNA genomes and an internal ribosomal entry site (IRES) element within their 5′-untranslated regions. To investigate the common host factors
Yutaro Ide, Bouchra Kitab, Nobumasa Ito, Riai Okamoto, Yui Tamura, Takafumi Matsui, Yoshihiro Sakoda, Kyoko Tsukiyama-Kohara   +7 more
doaj   +1 more source

Surgery and joint replacement for joint disease [PDF]

Acta Orthopaedica Scandinavica, 1998
(1998). Surgery and joint replacement for joint disease. Acta Orthopaedica Scandinavica: Vol. 69, The Bone and Joint Decade 2000–2010 for prevention of musculo-skeletal disorders: Lund, Sweden, April 17–18, 1998, pp. 17-20.
openaire   +4 more sources

Development of short hairpin RNA expression vectors targeting the internal ribosomal entry site of the classical swine fever virus genomic RNA

BMC Biotechnology, 2023
Background Classical swine fever (CSF) is a fatal contagious disease affecting pigs caused by classical swine fever virus (CSFV). The disease can be transmitted by pigs and wild boars, and it is difficult to prevent and control.
Riai Okamoto, Nobumasa Ito, Yutaro Ide, Bouchra Kitab, Yoshihiro Sakoda, Kyoko Tsukiyama-Kohara   +5 more
doaj   +1 more source

Deep segmentation leverages geometric pose estimation in computer-aided total knee arthroplasty

Healthcare Technology Letters, 2019
Knee arthritis is a common joint disease that usually requires a total knee arthroplasty. There are multiple surgical variables that have a direct impact on the correct positioning of the implants, and an optimal combination of all these variables is the
Pedro Rodrigues, Michel Antunes, Michel Antunes, Carolina Raposo, Pedro Marques, Fernando Fonseca, Joao P. Barreto   +6 more
doaj   +1 more source

Minimum 15-year results of metasul 28-mm metal-on-metal total hip arthroplasty in patients younger than 50 years of age

Journal of Orthopaedic Surgery and Research, 2021
Background Some propitious mid- and long-term studies had been reported for MoM bearings; however, most studies have addressed specific patient groups rather than younger, active patients, who probably represent the most suitable population for ...
Sheng-Yu Jin, Jing-Yao Jin, Joon-Kyoo Kang, Taek-Rim Yoon, Kyung-Soon Park   +4 more
doaj   +1 more source

DAS28: a useful instrument to monitor infliximab treatment in patients with rheumatoid arthritis [PDF]

, 2005
The Disease Activity Score using 28 joint counts (DAS28) has been developed in a cohort of patients with rheumatoid arthritis in which only conventional anti-rheumatic treatments were used. It has extensively been validated to monitor disease activity in
Fransen, Jaap, van Riel, Piet LCM
core   +2 more sources