Results 81 to 90 of about 12,189,357 (395)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Clinical evaluation of direct anterior approach total hip arthroplasty for severe developmental dysplasia of the hip

Scientific Reports, 2021
It is challenging to treat developmental dysplasia of the hip (DDH) classified Crowe III-IV using direct anterior approach (DAA) total hip arthroplasty (THA), and very little is known on its outcome. This study aimed to investigate the clinical result in
Zaiyang Liu, Courtney D. Bell, Alvin C. Ong, Jun Zhang, Jie Li, Yuan Zhang   +5 more
doaj   +1 more source

The use of intra-articular aneshesia as a diagnostic tool in canine lameness [PDF]

, 2012
Lameness in dogs may be difficult to localize because of mild pathologic changes or inconclusive clinical findings. Intra-articular anesthesia is proposed as a diagnostic method to localize the source of lameness.
Mosselmans, Lynn, Samoy, Yves, Van Ryssen, Bernadette, Van Vynckt, Delphine, Verhoeven, Geert, Verschooten, Francis   +5 more
core   +1 more source

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer's Disease Data. [PDF]

, 2019
There is well-documented evidence of brain network differences between individuals with Alzheimer's disease (AD) and healthy controls (HC). To date, imaging studies investigating brain networks in these populations have typically been cross-sectional ...
Alzheimer’s Disease Neuroimaging Initiative, Galvin, James, Guo, Ying, Kundu, Suprateek, Lukemire, Joshua, Wang, Yikai   +5 more
core   +2 more sources

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

Molecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns, Ulrik Ringborg, Julio Celis, Bengt Jönsson, Michael Baumann   +4 more
wiley   +1 more source

Clinical significance of small molecule metabolites in the blood of patients with different types of liver injury

Scientific Reports, 2021
To understand the characteristic of changes of serum metabolites between healthy people and patients with hepatitis B virus (HBV) infection at different stages of disease, and to provide reference metabolomics information for clinical diagnosis of liver ...
Hui Li, Yan Wang, Shizhao Ma, Chaoqun Zhang, Hua Liu, Dianxing Sun   +5 more
doaj   +1 more source

Non-Invasive Mouse Models of Post-Traumatic Osteoarthritis [PDF]

, 2015
SummaryAnimal models of osteoarthritis (OA) are essential tools for investigating the development of the disease on a more rapid timeline than human OA.
A.A. Pitsillides, Anderson, Armstrong, B.A. Christiansen, Batiste, Borella, Boyd, Brandt, Brodt, Brown, Carames, Chateauvert, Chateauvert, Chou, Christiansen, Christiansen, Chu, Crowninshield, D.R. Haudenschild, Das-Gupta, De Souza, De Souza, Diekman, Dirschl, Dunham, F. Guilak, Felson, Fitzgerald, Frankl, Funakoshi, Furman, Furman, Glasson, Guilak, Guingamp, Hashimoto, Hayami, Herzog, Holguin, Hui, Inoue, Jimenez, Jimenez, Jones, K.A. Lockwood, Kamekura, Karahan, Killian, Kimmerling, Ko, L.J. Sandell, Lewis, Lewis, Li, Little, Lockwood, Lodewyckx, Lohmander, Louer, Lynch, M.C.H. van der Meulen, M.J. Silva, Ma, Malfait, Malfait, Marcelon, Marsh, Marshall, Meacock, Messner, Moodie, Noyes, Oiestad, Onur, Palmoski, Palmoski, Pastoureau, Pond, Pottenger, Poulet, Poulet, Poulet, Roudier, S.A. Olson, Satkunananthan, Seifer, Shapiro, Suzuki, Teeple, Tiraloche, van Beuningen, van Beuningen, van Beuningen, van der Kraan, van der Kraan, van Osch, van Osch, van Osch, Wancket, Ward, Williams, Wong, Wu, Wu, Yang, Zaman, Zhou   +106 more
core   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Mechanisms underlying bone loss associated with gut inflammation [PDF]

, 2019
Patients with gastrointestinal diseases frequently suffer from skeletal abnormality, characterized by reduced bone mineral density, increased fracture risk, and/or joint inflammation.
Abu-Amer, Yousef, Arra, Manoj, Ke, Ke
core   +2 more sources

Progressive Myoclonus Epilepsy: Distinctive MRI Changes in Cerebellar and Motor Networks

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive myoclonus epilepsy (PME) is a rare generalized epilepsy syndrome with a well‐characterized genetic basis. The brain networks that are affected to give rise to the distinctive symptoms of PME are less well understood. Methods Eleven individuals with PME with a confirmed genetic diagnosis and 22 controls were studied.
Jillian M. Cameron, Remika Mito, Samuel F. Berkovic, Graeme D. Jackson   +3 more
wiley   +1 more source