Results 231 to 240 of about 11,174,931 (323)

Mesenchymal stem cell-derived extracellular vesicles in joint diseases: Therapeutic effects and underlying mechanisms. [PDF]

open access: yesJ Orthop Translat
Wu J   +15 more
europepmc   +1 more source

DNA Barcoding‐Enabled Tracking of Lipid Nanoparticles: Drug‐Loading‐Dependent Biodistribution and Tumor Microenvironment Targeting

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu   +5 more
wiley   +1 more source

Explainable deep learning for disease activity prediction in chronic inflammatory joint diseases. [PDF]

open access: yesPLOS Digit Health
Trottet C   +9 more
europepmc   +1 more source

Role of Interleukin-36 in inflammatory joint diseases. [PDF]

open access: yesZhejiang Da Xue Xue Bao Yi Xue Ban, 2023
Wang C, Hu J, Shi J.
europepmc   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah   +9 more
wiley   +1 more source

Pyroptosis: A spoiler of peaceful coexistence between cells in degenerative bone and joint diseases. [PDF]

open access: yesJ Adv Res
Li Z   +10 more
europepmc   +1 more source

Cardiovascular Magnetic Resonance Detects Inflammatory Cardiomyopathy in Symptomatic Patients with Inflammatory Joint Diseases and a Normal Routine Workup. [PDF]

open access: yesJ Clin Med, 2022
Markousis-Mavrogenis G   +9 more
europepmc   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun   +9 more
wiley   +1 more source

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