Results 191 to 200 of about 2,089,020 (348)

Inhibition of Heat Shock Protein 90β by Catalpol: A Potential Therapeutic Approach for Alleviating Inflammation‐Induced Cartilage Injuries in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
The schematic diagram delineates the chondroprotective effects of Ca‐bMSN in OA models. The upper portion of the diagram depicts the synthesis process of Ca‐bMSN. The lower section illustrates the post‐injection of Ca‐bMSN in joint cavity, catalpol released and subsequently mediates the reduction of oxidative stress, ECM catabolism, apoptosis, and ...
Zhenwei Zhou   +14 more
wiley   +1 more source

Temporomandibular joint sounds and disc dislocations incidence after orotracheal intubation

open access: yesClinical, Cosmetic and Investigational Dentistry, 2009
Estela T Rodrigues1, Iván C Suazo2, Antonio S Guimarães31Centro de Pós Graduação em Odontologia São Leopoldo Mandic, Campinas, Brasil; 2Department of Morphology.
Estela T Rodrigues   +2 more
doaj  

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv   +8 more
wiley   +1 more source

Asymmetric bilateral hip dislocations and unilateral femoral head fracture: A CASE report

open access: yesTrauma Case Reports, 2018
Hip is a stabilized joint due to the surrounding ligaments, and muscles, which can dislocate as a result of high energy trauma, high-level falls, and motor vehicle accidents.
Erdem Değirmenci   +2 more
doaj  

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

open access: yesAdvanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie   +9 more
wiley   +1 more source

Revision Acromioclavicular-Coracoclavicular Reconstruction: Use of Precontoured Button and 2 Allografts

open access: yesArthroscopy Techniques, 2017
Injuries to the acromioclavicular (AC) joint are common, particularly in the young and active population. Approximately 9% of all shoulder girdle injuries involve the AC joint, and AC joint dislocations represent approximately 8% of all joint ...
Daniel B. Haber, M.D.   +5 more
doaj  

Wireless In Situ Catalytic Electron Signaling‐Mediated Transcriptomic Reprogramming for Neuron Regeneration via Adaptable Antennas

open access: yesAdvanced Science, EarlyView.
A wireless‐charging sustained oxygen release from conductive microgels (SOCO) served as an antenna and an on‐demand O2 release for nerve regeneration is developed. Introducing “electromagnetic messenger”, using external alternating magnetic field (AMF) to enhance catalytic oxygen release and electrical stimulation to promote the reconstruction of blood
Hoi Man Iao   +15 more
wiley   +1 more source

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