Results 191 to 200 of about 66,296 (329)

Modulating Macrophage–Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration

open access: yesAdvanced Science, EarlyView.
The G‐CS/MSN drug delivery system enhances intervertebral disc repair through sequential drug release. Abstract Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM).
Xiangzhen Kong   +12 more
wiley   +1 more source

Complex metacarpophalangeal joint dislocations management with dorsal extensor sparing approach

open access: yesJournal of Orthopaedic Reports
Metacarpophalangeal (MCP) joint dislocations, though rare, pose unique challenges in their management. Surgical intervention is typically necessary for complex cases, with both volar and dorsal approaches available, each with distinct advantages and ...
Rajesh Kishanrao Ambulgekar   +3 more
doaj  

Knee joint dislocations-Current epidemiology and treatment in Germany. [PDF]

open access: yesKnee Surg Sports Traumatol Arthrosc
Weber J   +5 more
europepmc   +1 more source

Mitochondria‐Targeted ROS Scavenging Natural Enzyme Cascade Nanogels for Periodontitis Treatment via Hypoxia Alleviation and Immunomodulation

open access: yesAdvanced Science, EarlyView.
TPP‐SAT, a mitochondria‐targeted natural enzyme‐cascade nanogel, selectively scavenges mitochondrial ROS (e.g., H2O2/·O2⁻) and converts them into therapeutic O2 via enzymatic cascades, alleviating hypoxia and inflammation. It rebalances M1/M2 macrophage polarization, activates the Nrf2 pathway while suppressing NF‐κB, enhances antioxidant defenses, and
Yanfen Zheng   +6 more
wiley   +1 more source

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