Results 281 to 290 of about 2,089,020 (348)
Objective The sparse effector “omnigenic” hypothesis postulates that the polygenic effects of common single nucleotide polymorphisms (SNPs) on a typical complex trait are mediated by trans effects that coalesce on expression of a relatively sparse set of core genes.
Athina Spiliopoulou+9 more
wiley +1 more source
Gout and NLRP3 inflammasome biology
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilisation, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal‐induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley +1 more source
DISLOCATION OF THE PROXIMAL TIBIOFIBULAR JOINT HANDBALL 1560
A. R. Bickelhaupt
openalex +1 more source
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun+19 more
wiley +1 more source
Abstract In today's digital age, misinformation propagates rapidly through digital channels, blurring the lines between truth and fiction, and challenging the foundations of trust in information sources. Although affecting all spheres of life, misinformation poses a significant threat to workers highlighting a critical intersection between ...
Ashwani Malhotra+4 more
wiley +1 more source
Abstract This study addresses significant process challenges associated with the reactive nature of hemicellulose‐derived furan intermediates in aqueous mediums. A continuous agitated cell reactor was used to intensify the extractive reaction using methyl isobutyl ketone as an extractive phase to isolate in situ the furan products obtained by ...
Abdullahi Adamu+2 more
wiley +1 more source
Activism as education in and through the youth climate justice movement
Abstract Young people worldwide are increasingly participating in a global movement for climate justice, yet to date, little research has examined how youth climate justice activists conceive of and experience activism as education. The present study used in‐depth, semi‐structured interviews with 16 US climate justice activists (aged 15–17) to address ...
Carlie D. Trott
wiley +1 more source
A cross‐cultural examination of elementary students' perceptions of academic feedback
Abstract With a growing emphasis on students playing an active role in the feedback process, understanding how students perceive academic feedback is essential to support the implementation of relevant strategies that can drive better engagement. The current study explored elementary school students' perceptions of feedback in two different contexts ...
Alexandra Troy+4 more
wiley +1 more source
Development of Medial Subtalar Dislocation after Sports Injury: A Case Report
Serdar Hakan Başaran+2 more
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