Results 51 to 60 of about 5,638,528 (351)

When good bugs go bad: Epidemiology and antimicrobial resistance profiles of Corynebacterium striatum, an emerging multidrug-resistant, opportunistic pathogen [PDF]

open access: yes, 2017
Infections with Corynebacterium striatum have been described in the literature over the last 2 decades, with the majority being bacteremia, central line infections, and occasionally, endocarditis.
Anderson, Neil   +4 more
core   +2 more sources

The Different Microbial Etiology of Prosthetic Joint Infections according to Route of Acquisition and Time after Prosthesis Implantation, Including the Role of Multidrug-Resistant Organisms

open access: yesJournal of Clinical Medicine, 2019
The aim of our study was to characterize the etiology of prosthetic joint infections (PJIs)—including multidrug-resistant organisms (MDRO)—by category of infection. A multicenter study of 2544 patients with PJIs was performed.
N. Benito   +26 more
semanticscholar   +1 more source

Tolerance of Prolonged Oral Tedizolid for Prosthetic Joint Infections: Results of a Multicentre Prospective Study

open access: yesAntibiotics, 2020
Objectives: Data on clinical and biological tolerance of tedizolid (TZD) prolonged therapy are lacking. Methods: We conducted a prospective multicentre study including patients with prosthetic joint infections (PJIs) who were treated for at least 6 weeks
Eric Senneville   +5 more
doaj   +1 more source

Prosthetic joint infections [PDF]

open access: yes, 2013
Objectives: To review the available literature on prosthetic joint infections and provide recommendations on management particularly the importance of identifying the causative organism and starting the most appropriate antimicrobial therapy.
Fsadni, Claudia, Fsadni, Peter
core  

Is Helicobacter Pylori Associated with a Migraine? [PDF]

open access: yes, 2017
Objective: To determine whether Helicobacter pylori (H. pylori) is associated with migraine headache. Design: Case-control study. Settings: Local tertiary Hospitals in Cairo, Egypt and in HaferAlbaten, Saudi Arabia.
Ali Radwa A   +2 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Septic Arthritis Caused by Legionella dumoffii in a Patient with Systemic Lupus Erythematosus-Like Disease [PDF]

open access: yes, 2011
We describe a patient with systemic lupus erythematosus (SLE)-like disease on immunosuppressive treatment who developed septic arthritis of the knee involving Legionella dumoffii. Cultures initially remained negative. A broad-range 16S PCR using synovial
Flendrie, M.   +5 more
core   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Adult native septic arthritis: a review of 10 years of experience and lessons for empirical antibiotic therapy. [PDF]

open access: yes, 2011
Objectives To review the epidemiology of native septic arthritis to establish local guidelines for empirical antibiotic therapy as part of an antibiotic stewardship programme.
Clerc, O.   +4 more
core   +1 more source

Culture-negative periprosthetic joint infections

open access: yesEFORT Open Reviews, 2019
Culture-negative periprosthetic joint infections (CN-PJI) pose a significant challenge in terms of diagnosis and management. The reported incidence of CN-PJI is reported to be between 7% and 15%.
J. Palan   +5 more
semanticscholar   +1 more source

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