Results 261 to 270 of about 2,939,482 (385)

Harnessing Work Function Modulation for Hydrogen Evolution Catalysis in Mesoporous Bimetallic Pt‐M Alloys: The Role of Mesopores in Work Function Optimization

open access: yesAdvanced Science, EarlyView.
This study presents mesoporous binary Pt‐M alloy films (m‐Pt‐M, M = Pd, Rh, and Ru) with uniform porosity and tailored work functions (WFs) as an experimental study platform. The WFs of the m‐Pt‐M films exhibit a volcano‐type relationship with their HER performance.
Lei Fu   +10 more
wiley   +1 more source

The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression

open access: yesAdvanced Science, EarlyView.
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu   +5 more
wiley   +1 more source

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

open access: yesAdvanced Science, EarlyView.
This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang   +10 more
wiley   +1 more source

Natural Fiber@MXene‐Engineered Chitosan Aerogels: Thermodynamic‐Transport Synergy for Solar‐Driven Hypersaline Interfacial Evaporation

open access: yesAdvanced Science, EarlyView.
The natural fiber@MXene‐engineered chitosan aerogel with hierarchically oriented channels is developed in this study. The photon‐entrapping networks cooperated with oriented channels to facilitate water transport and improve solar‐thermal/environmental energy synergy, endowing an evaporation rate up to 4.40 kg m−2 h−1 and efficient salt rejection ...
Qin Su   +11 more
wiley   +1 more source

Radiomics‐Based Unsupervised Clustering Identifies Subtypes Associated With Prognosis and Immune Microenvironment in Clear Cell Renal Cell Carcinoma: A Multicenter Study

open access: yesAdvanced Science, EarlyView.
This study developed an unsupervised radiomics system integrating CT imaging and multi‐omics data to stratify clear cell renal cell carcinoma into two subtypes with distinct clinical outcomes. Cluster 1 showed lower recurrence risk and active immunity, while Cluster 2 exhibited higher recurrence risk, enriched VHL/KDM5C mutations, immunosuppressive ...
Yusheng Guo   +14 more
wiley   +1 more source

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