Results 191 to 200 of about 2,895,344 (297)

Association of Sleep Disorders with Temporomandibular Joint Pain Dysfunction Syndrome. [PDF]

J Pharm Bioallied Sci
Albadi MAA, Abuthnain MM, Alshahrani MMA, Alrajhi JFA, Alshehri GMJ, Issrani R.   +5 more
europepmc   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Perceptions regarding the use of cannabis in orthopaedics for treating musculoskeletal joint pain: A survey of arthritis patients. [PDF]

J Int Med Res
Gjorgjievski M, Madden K, Tushinski D, Adili A, Bullen C, Koziarz F, Koziarz A, de Freitas L, Li S, Bhandari M, Johal H.   +10 more
europepmc   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

Evaluating the Implementation Fidelity of the REJOIN (Using Exercise to Relieve Joint Pain and Improve Aromatase Inhibitor Adherence in Older Breast Cancer Survivors) Pilot Trial. [PDF]

J Appl Gerontol
Coffman EM, Zakrzewski SG, Leitzelar BN, Peters CH, Zimmer RP, Bluethmann SM.   +5 more
europepmc   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

Efficacy of endoscopic dorsal medial branch radiofrequency ablation combined with manual therapy for chronic lumbar facet joint pain. [PDF]

Front Rehabil Sci
Hu Y, Liu Y, Zhong D, Wu S, Wang Y.
europepmc   +1 more source

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

Advanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan, Xinzhe Feng, Chuanju Liu, Jianfei Tong, Zhi Li, Chenxu Liu, Yutong Dong, Chen Meng, Yihong Xu, Weidong Xu   +9 more
wiley   +1 more source

Circulating miR-146a-5p and miR-98-5p as Indicators of Inflammatory Response and Joint Pain in Chikungunya Fever. [PDF]

Virus Res
Xie D, Ling S, Lu L, Huang Y, Huang H, Huang Y, Yi S, Liu Z.   +7 more
europepmc   +1 more source