Results 31 to 40 of about 20,442 (218)

Peptide regulation of plant cell homeostasis [PDF]

BIO Web of Conferences
Homeostasis acts as a fundamental characteristic of living organisms and is understood as maintaining the internal environment within acceptable limits. Various classes of plant signal peptides are involved in the regulation of plant homeostasis. The aim
Linkova Natalia, Diatlova Anastasiia, Dudkov Aleksander   +2 more
doaj   +1 more source

Performance assessment of railway track under the impact of longitudinal forces during the implementation of maximum traction modes when using electric locomotives with an asynchronous traction drive

Вестник Научно-исследовательского института железнодорожного транспорта, 2020
Strategic task of increasing carrying capacity of railways requires a constant increase in the mass of trains due to the passage of heavy and coupled trains.
V. O. Pevzner, V. V. Kochergin, V. V. Tret'yakov, K. V. Kolesnikov, E. A. Polunina   +4 more
doaj   +1 more source

Railway Science: Results of the I International Scientific and Practical Conference “Research 1520 VNIIZHT: Look Beyond the Horizons”

Вестник Научно-исследовательского института железнодорожного транспорта, 2021
In a constantly changing world, any production activity, including transport, requires scientific support, which, in turn, involves the active participation of scientists, as well as the possibility of exchanging views between theorists and practitioners.
A. B. Kosarev, O. N. Rimskaya, I. V. Anokhov, A. V. Zarucheyskiy, N. M. Gorshkov   +4 more
doaj   +1 more source

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

Advanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐Yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi   +12 more
wiley   +1 more source

Changes in the Interaction Properties of Antibodies with Fc Receptors upon Binding to Target Antigens

Biosensors
The interaction of therapeutic antibodies with Fc receptors is an important property that is actively modified to improve pharmacokinetic profiles and optimize antibody-dependent mechanisms of action.
Artem S. Grevtsev, Anton A. Kommer, Irina S. Zelmanchuk, Andrei S. Avdiushkin, Elizaveta O. Ermolaeva, Aleksandr A. Tiulin, Darya O. Chernyshova, Alexandra D. Azarian, Alexandr A. Gordeev, Aleksey K. Misorin   +9 more
doaj   +1 more source

THE FEATURES OF THE INDICATOR MINERALS OF KIMBERLITES IN A NEW PIPE YANVARSKAJA (WESTERN YAKUTIA)

Известия высших учебных заведений: Геология и разведка, 2017
The first results of the mineral-petrographic studies of microclastes of kimberlites from the basal horizon of the Upper Paleozoic deposits of the Alakit-Markhinsky kimberlite field (Western Yakutia) have been presented.
D. V. Ivanov, V. V. Ivanov, A. V. Tolstov   +2 more
doaj   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

Methods of Financial Literature Assessment: Kazakhstan’s Experience

Экономика: стратегия и практика, 2022
This research aims to study foreign experience and review the literature on methods for assessing financial literacy levels. Including analysis of financial literacy level in Kazakhstan based on official data from the AFRD.
K. Y. Khassenova, G. K. Ismailova, L. Z. Parimbekova, B. Kuantkan, N. M. Anarbekov   +4 more
doaj   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source