Results 221 to 230 of about 1,544,227 (288)

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

open access: yesAdvanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong   +11 more
wiley   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

open access: yesAdvanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian   +13 more
wiley   +1 more source

Low Latency Global Carbon Budget Reveals Late 2024 Carbon Losses and Contrasting Early 2025 Land Sink Recovery Signals

open access: yesAdvanced Science, EarlyView.
Low latency carbon budget estimates for July 2024–June 2025 combine atmospheric CO2 growth rates, fossil emissions, ocean uptake, DGVM land fluxes, and OCO‐2 inversions. The budget shows that late‐2024 land carbon losses dominate the annual anomaly, while early‐2025 recovery differs between bottom‐up models and top‐down inversions, especially in ...
Piyu Ke   +32 more
wiley   +1 more source

From Biomechanics to Metallobiology: A Bibliometric Mapping of Ferroptosis and Trace Elements in Osteoarthritis (2014-2024). [PDF]

open access: yesBiol Trace Elem Res
Qin TH   +10 more
europepmc   +1 more source

Triple-interlocked-nanotwinned bulk magnesium alloys with exceptional strength and ageing resistance. [PDF]

open access: yesNat Commun
Peng Q   +14 more
europepmc   +1 more source

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