Results 171 to 180 of about 1,486,726 (286)

The Plant‐to‐Plant Circular Strategy: Coupling Photodegradation and Phytoremediation With Plant‐Based Nanomaterials for Plastic Degradation

open access: yesAdvanced Science, EarlyView.
Plant‐based nanomaterials derived from alfalfa serve as dual‐function catalysts, coupling photodegradation and phytoremediation to degrade polyethylene under UV‐A light and in soil. The nanomaterials work synergistically with alfalfa and soil microbes, achieving efficient plastic breakdown without trophic transfer.
Haoran Liu   +4 more
wiley   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

open access: yesAdvanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang   +7 more
wiley   +1 more source

Temporal Decoupling: A New Paradigm of 4D Photo‐Responsive Carbon Dots Films With Modular Regulation of Color and Deformation

open access: yesAdvanced Science, EarlyView.
This work demonstrates a novel energy regulation strategy using the long‐lived S₁ state as a “kinetic capacitor” to achieve temporally decoupled integration of photoinduced deformation and multicolor fluorescence in naphthalimide‐functionalized carbon dots. This dual‐channel programmable shunting of excited‐state energy establishes a dynamic single‐use
Jianye Zhang   +6 more
wiley   +1 more source

Paraborg: Paramedic Cyborg Insects for In Situ Emergency Drug‐Delivery

open access: yesAdvanced Science, EarlyView.
This work introduces Paraborg, a human‐supervised paramedic cyborg‐insect platform that combines controllable locomotion, onboard imaging, and an auto‐injection mechanism for in situ drug‐delivery. By demonstrating reliable navigation, target stabilization, injector launch, and multi‐insect teamwork, the study extends cyborg insects from survivor ...
H. Nhan Le   +5 more
wiley   +1 more source

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

open access: yesAdvanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao   +8 more
wiley   +1 more source

Robust Stitching Interface and Deep Learning Empowered Hydrogel Human‐Machine Interface

open access: yesAdvanced Science, EarlyView.
A molecular design strategy is presented that exploits synergistic carboxylate anion–quaternary ammonium interactions to simultaneously strengthen the hydrogel–PET interface and the bulk hydrogel network. Integrated with deep learning signal processing, the stable hydrogel–PET interface enables consistent signal acquisition and reliable human‐machine ...
Hao Dong   +11 more
wiley   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

open access: yesAdvanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang   +10 more
wiley   +1 more source

Bio‐Based Polyurethanes for Sustainable and Multifunctional Applications

open access: yesAdvanced Science, EarlyView.
Bio‐based polyurethanes prepared from vegetable oils, lignin, and polysaccharides have attracted increasing interest as alternatives to fossil‐derived polyurethanes. This review summarizes recent progress in their chemistry, structural engineering, and advanced applications, highlighting the roles of feedstocks, chain‐segment design, dynamic covalent ...
Xin Li   +6 more
wiley   +1 more source

Multi‐Omics Integration Identifies a CDH3‐Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors

open access: yesAdvanced Science, EarlyView.
Single‐cell, spatial, molecular, and pathology analyses identify a CDH3‐associated malignant epithelial state in thymic epithelial tumors. This state links stem‐like and EMT programs to M2 macrophage–rich immunosuppressive niches, genomic instability, poor survival, and drug vulnerability.
Yuntao Feng   +13 more
wiley   +1 more source

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