Results 61 to 70 of about 2,048 (300)

APPLICATION OF POINT INTERPOLATION METHOD IN JOINTED ROCK MASS

open access: yes, 2011
In this paper, point interpolation method (PIM) is applied to analyze the nonlinear and elastoplastic behavior of jointed rock masses. PIM is advantageous over the other meshless methods that are based on moving least square (MLS) technique. On the other
M. HAJIAZIZI, M. R. ASHORY
core   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Model Test Study on Cylindrical Blasting Stress Wave Propagation across Jointed Rock Mass with Different Initial Stresses

open access: yesAdvances in Civil Engineering, 2020
In the drilling and blasting excavation of underground rock mass, the stress wave produced by the blasting holes usually propagates in the form of cylindrical wave, while the rock mass surrounding the underground engineering is initially subjected to the
Qian Dong, XinPing Li, JunHong Huang
doaj   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

open access: yesAdvanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao   +7 more
wiley   +1 more source

Fracture Behavior of Rock with Initial Damage: Theoretical, Experimental, and Numerical Investigations

open access: yesGeofluids, 2020
Geomaterials such as rock mass often have initial damage under the influence of long-term geological action and hydration corrosion environment. The initial damage affects the integrity and stability of the rock mass, resulting in a difference in the ...
Hui Zhang   +6 more
doaj   +1 more source

Intelligent Models Applied to Elastic Modulus of Jointed Rock Mass

open access: yes, 2018
Elastic Modulus (Ej) of jointed rock mass is a key parameter for deformation analysis of rock mass. This chapter adopts three intelligent models {Extreme Learning Machine (ELM), Minimax Probability Machine Regression (MPMR) and Generalized Regression ...
Sanjiban Sekhar Roy   +3 more
core   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun   +19 more
wiley   +1 more source

Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design

open access: yesAdvanced Science, EarlyView.
A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram   +4 more
wiley   +1 more source

Photoelectric‐Coupled Ferroelectric Heterojunctions for Ultrahigh NO2 Sensing With Polarization‐Memory‐Assisted Interfacial Modulation

open access: yesAdvanced Science, EarlyView.
This study demonstrates a Bi2WO6/SrBi2Ta2O9 heterojunction where light‐driven ferroelectric polarization reversal couples with persistent photoconductivity, enabling exclusive NO2 selective room‐temperature sensing. The device achieves a two‐order‐of‐magnitude sensitivity enhancement over an unpolarized device, a sub‐ppb detection limit, and robust ...
Liping Tan   +11 more
wiley   +1 more source

Facile Fabrication of Low‐Impedance, Highly Conformal Epidermal Electrodes Based on Laser‐Induced Graphene–Silver Nanocomposites

open access: yesAdvanced Science, EarlyView.
A facile laser‐induced graphene–silver nanocomposite strategy enables ultrathin epidermal electrodes with low impedance, high conductivity, and excellent mechanical robustness. The porous LIG–Ag conductive network mechanically interlocked with SEBS provides stable, motion‐resistant biopotential monitoring, enabling high‐fidelity ECG, EMG, and EEG ...
Jiuqiang Li   +6 more
wiley   +1 more source

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