Results 111 to 120 of about 242,536 (298)
Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform
Advanced Science, EarlyView.We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng +5 more
wiley +1 more source
The European Journal of Humour Research, 2021 A prominent humour theory suggests that most jokes will violate a subjective moral principle. This paper explores the ramifications of Thomas Veatch’s social violations theory of humour, and hypothesizes that jokes tend to produce four distinct humour ...
Joseph Polimeni
doaj
, 2013 There is a problem on our campus—a problem of sexual assault and its perpetuation due to unnecessary silence. Current compulsory education on the topic through AlcoholEdu and First-Year Orientation are often turned into jokes because of course everyone ...
Connelly, Sarah M.
core
Advanced Science, EarlyView.Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
Definitions of the humorous in Chris Rock and Russell Peters fan blogs: A discussion of the problem of incongruity [PDF]
, 2011 There is an old and unsolved problem in the philosophy of humour that examines the conditions under which some incongruities are deemed funny and some are not.
Weaver, S
core
A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair
Advanced Science, EarlyView.A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao +14 more
wiley +1 more source
, 2013 Some humor is offensive, but does this convey a moral constraint on what comedians can include in their jokes? Using stand up bits and reflections on comedy from George Carlin, Louis C.K., and Doug Stanhope, various philosophies of humor, and the ...
Garrett, James H.
core
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT In recent decades, agriculture has become increasingly concentrated through horizontal mergers and acquisitions via corporate entities, and policy makers are concerned this will be exacerbated by the aging population of farm operators. To reduce market concentration in agriculture, many states have enacted policies to entice new prospective ...
Justin M. Ross +2 more
wiley +1 more source
Bisociative ludos: the wondrous tales of eupalinos ugajin and naxos loon [PDF]
, 2011 This text proposes to examine the virtual lives and creative activities of two metaverse avatars, Eupalinos Ugajin and Naxos Loon, by examining the correlations between their acts of creation and the notion of ‘play’.
Ayiter, Elif
core +1 more source
Is This a Joke? Detecting Humor in Spanish Tweets
, 2017 While humor has been historically studied from a psychological, cognitive and linguistic standpoint, its study from a computational perspective is an area yet to be explored in Computational Linguistics.
A Reyes +11 more
core +1 more source