Results 11 to 20 of about 33,113 (184)

Lessons from the PROTECT-CH COVID-19 platform trial in care homes

Health Technology Assessment
Background Coronavirus disease-2019 was associated with significant mortality and morbidity in care homes in 2020–1. Repurposed antiviral drugs might reduce morbidity and mortality through reducing viral transmission, infection, replication and ...
Philip M Bath, Jonathan Ball, Matthew Boyd, Heather Gage, Matthew Glover, Maureen Godfrey, Bruce Guthrie, Jonathan Hewitt, Robert Howard, Thomas Jaki, Edmund Juszczak, Daniel Lasserson, Paul Leighton, Val Leyland, Wei Shen Lim, Pip Logan, Garry Meakin, Alan Montgomery, Reuben Ogollah, Peter Passmore, Philip Quinlan, Caroline Rick, Simon Royal, Susan D Shenkin, Clare Upton, Adam L Gordon   +25 more
doaj   +2 more sources

Development of a succinyl CoA:3-ketoacid CoA transferase inhibitor selective for peripheral tissues that improves glycemia in obesity [PDF]

iScience
Summary: Many individuals with type 2 diabetes (T2D) cannot take current therapies due to their adverse effects. Thus, new glucose-lowering agents targeting unique mechanisms are needed.
Seyed Amirhossein Tabatabaei Dakhili, Kunyan Yang, Hamdah Al Nebaihi, Amanda A. Greenwell, Melinda Wuest, Jenilee Woodfield, Rabih Abou Farraj, Christina T. Saed, Jordan S.F. Chan, Rakesh K. Bhat, Indiresh A. Mangra-Bala, Tanin Shafaati, Keshav Gopal, Farah Eaton, Sally R. Ferrari, Cory S. Wagg, Megan E. Capozzi, Jonathan E. Campbell, Michael Overduin, Carlos A. Velazquez-Martinez, J. N. Mark Glover, Frank Wuest, Dion R. Brocks, John R. Ussher   +23 more
doaj   +2 more sources

Inconsistencies in mapping current distribution in transcranial direct current stimulation

Frontiers in Neuroimaging, 2023
IntroductiontDCS is a non-invasive neuromodulation technique that has been widely studied both as a therapy for neuropsychiatric diseases and for cognitive enhancement.
Anita S. Jwa, Jonathan S. Goodman, Gary H. Glover   +2 more
doaj   +1 more source

Predictive value of the National Early Warning Score 2 for hospitalised patients with viral respiratory illness is improved by the addition of inspired oxygen fraction as a weighted variable

BMJ Open Respiratory Research, 2023
Objectives The National Early Warning Score 2 (NEWS2) is validated for predicting acute deterioration, however, the binary grading of inspired oxygen fraction (FiO2) may limit performance.
Jonathan Clarke, David Grant, Guy Glover, Nishita Desai, Jack Gallifant   +4 more
doaj   +1 more source

Investigating mechanisms of fast BOLD responses: The effects of stimulus intensity and of spatial heterogeneity of hemodynamics

NeuroImage, 2021
Recent studies have demonstrated that fast fMRI can track neural activity well above the temporal limit predicted by the canonical hemodynamic response model.
Jingyuan E. Chen, Gary H. Glover, Nina E. Fultz, Bruce R. Rosen, Jonathan R. Polimeni, Laura D. Lewis   +5 more
doaj   +1 more source

Managing residents in difficulty within CBME residency educational systems: a scoping review

BMC Medical Education, 2020
Background Best practices in managing residents in difficulty (RID) in the era of competency-based medical education (CBME) are not well described. This scoping review aimed to inventory the current literature and identify major themes in the articles ...
Jonathan Pirie, Lisa St. Amant, Susan Glover Takahashi   +2 more
doaj   +1 more source

Exploring the impact of pulse oximeter selection within the COVID-19 home-use pulse oximetry pathways

BMJ Open Respiratory Research, 2022
Background During the COVID-19 pandemic, portable pulse oximeters were issued to some patients to permit home monitoring and alleviate pressure on inpatient wards. Concerns were raised about the accuracy of these devices in some patient groups.
David Stell, Guy Glover, Jonathan James Noble, Rebecca Hazell Kay, Man Ting Kwong, Michael John Russell Jeffryes, Liam Johnston, Emmanuel Akinluyi   +7 more
doaj   +1 more source

A ten-year community reporting database reveals rising coyote boldness and associated human concern in Edmonton, Canada

Ecology and Society, 2023
In cities throughout North America, sightings of coyotes (Canis latrans) have become common. Reports of human-coyote conflict are also rising, as is the public demand for proactive management to prevent negative human-coyote interactions.
Jonathan J. Farr, Matthew J. Pruden, Robin D. Glover, Maureen H. Murray, Scott A. Sugden, Howard W. Harshaw, Colleen Cassady St. Clair   +6 more
doaj   +1 more source

Carbon leakage and the argument from no difference [PDF]

, 2015
Critics of carbon mitigation often appeal to what Jonathan Glover has called ‘the argument from no difference’: that is, ‘if I don’t do it, someone else will’. Yet even if this justifies continued high emissions by the industrialised countries, it cannot
Rendall, Matthew
core   +3 more sources

Pseudopolymorphism in Brucine: Brucine-Water (1/2), The Third Crystal Hydrate of Brucine [PDF]

, 2007
The structure of the third pseudopolymorphic hydrate of brucine, brucine-water (1/2) [systematic name 2,3-dimethoxystrychnidin-10-one-water (1/2)], C23H26N2O4 . 2H2O, has been determined at 130 K.
Smith, Graham, Wermuth, Urs, White, Jonathan   +2 more
core   +2 more sources