Results 41 to 50 of about 33,127 (206)

Markers of skeletal muscle mitochondrial function and lipid accumulation are moderately associated with the homeostasis model assessment index of insulin resistance in obese men. [PDF]

open access: yesPLoS ONE, 2013
Lower skeletal muscle mitochondrial oxidative phosphorylation capacity (OXPHOS) and intramyocellular lipid (IMCL) accumulation have been implicated in the etiology of insulin resistance (IR) in obesity. The purpose of this study was to examine the impact
Imtiaz A Samjoo   +10 more
doaj   +1 more source

Patient-reported outcomes, postoperative pain and pain relief after day-case surgery (POPPY): chronic post-surgical pain prevalence and associations. [PDF]

open access: yesAnaesthesia
Summary Introduction Day‐case surgical activity is increasing in the UK yet there is a lack of data on the prevalence of chronic post‐surgical pain in this population. This study uses data from the POPPY study to estimate the prevalence of chronic post‐surgical pain after day‐case surgery, its relationship with quality of life and also explores ...
Brayne AB   +9 more
europepmc   +2 more sources

Study protocol: a multicentre, open-label, parallel-group, phase 2, randomised controlled trial of autologous macrophage therapy for liver cirrhosis (MATCH)

open access: yesBMJ Open, 2021
Introduction Liver cirrhosis is a growing global healthcare challenge. Cirrhosis is characterised by severe liver fibrosis, organ dysfunction and complications related to portal hypertension.
Catriona Graham   +16 more
doaj   +1 more source

Estimating the returns to United Kingdom publicly funded musculoskeletal disease research in terms of net value of improved health outcomes

open access: yesHealth Research Policy and Systems, 2018
Background Building on an approach applied to cardiovascular and cancer research, we estimated the economic returns from United Kingdom public- and charitable-funded musculoskeletal disease (MSD) research that arise from the net value of the improved ...
Matthew Glover   +6 more
doaj   +1 more source

Intestinal parasitic infections and risk factors: a cross-sectional survey of some school children in a suburb in Accra, Ghana

open access: yesBMC Research Notes, 2017
Objective This study aimed to determine the prevalence and establish some risk factors associated with the acquisition of gastrointestinal parasitic infections in school children in Accra, Ghana.
Akua Obeng Forson   +5 more
doaj   +1 more source

L’exigence de cohérence éthique chez Jonathan Glover

open access: yesRevue d’études benthamiennes, 2019
Si l’exigence de coherence, entendue comme non-contradiction, semble traverser les domaines et etre entendue aussi bien dans le champ theorique que dans la pratique, il n’en demeure pas moins que le passage de l’un a l’autre peut induire des distorsions sur lesquelles nous trouvons, dans la pensee pratique et appliquee de Jonathan Glover, des ...
openaire   +2 more sources

Book review: culture by Terry Eagleton [PDF]

open access: yes, 2016
In Culture, literary and cultural critic Terry Eagleton turns his attention to defining and pinpointing the role that culture plays in our lives as well as its value, traversing examples including Edmund Burke, Jonathan Swift and Oscar Wilde.
Glover, Danni
core  

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

open access: yesAngewandte Chemie International Edition, EarlyView.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp   +29 more
wiley   +1 more source

Corrective Justice and Liability for Global Warming [PDF]

open access: yes, 2007
This report addresses the environmental discourse of the current comprehensive plan of Stockholm, The Walkable City, and in what ways it can be developed following an ecofeminist framework. With a foundation in a critical perspective on current processes
Adler, Matthew D.
core   +3 more sources

Study protocol for a non-inferiority trial of cytisine versus nicotine replacement therapy in people motivated to stop smoking

open access: yesBMC Public Health, 2011
Background Smokers need effective support to maximise the chances of successful quit attempts. Current smoking cessation medications, such as nicotine replacement therapy (NRT), bupropion, nortriptyline or varenicline, have been shown to be effective in ...
Walker Natalie   +9 more
doaj   +1 more source

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