Results 31 to 40 of about 2,135 (129)

Global Brain Transcriptome Analysis of a Neuronal Ceroid Lipofuscinoses Mouse Model

open access: yesASN Neuro, 2019
In humans, homozygous mutations in the TPP1 gene results in loss of tripeptidyl peptidase 1 (TPP1) enzymatic activity, leading to late infantile neuronal ceroid lipofuscinoses disease.
Miriam S. Domowicz   +7 more
doaj   +1 more source

Mechanisms of the QBO Influence on the Tropical Troposphere: Modulation by ENSO Conditions

open access: yesJournal of Geophysical Research: Atmospheres, Volume 131, Issue 13, 16 July 2026.
Abstract The Quasi‐Biennial Oscillation (QBO) is the dominant mode of tropical stratospheric variability that can influence tropospheric circulation and convection. El Niño‐Southern Oscillation (ENSO), which is the primary source of interannual variability in the tropical troposphere, can modulate both the QBO and its impact on the tropical troposphere.
Mario Rodrigo   +4 more
wiley   +1 more source

The level of DING proteins is increased in HIV-infected patients: in vitro and in vivo studies.

open access: yesPLoS ONE, 2012
DING proteins constitute an interesting family, owing to their intriguing and important activities. However, after a decade of research, little is known about these proteins.
Ahmed Djeghader   +16 more
doaj   +1 more source

Enhancing the Ethical Culture of Organizations: A Longitudinal Study Using a Comprehensive Ethics Training

open access: yesBusiness Ethics, the Environment &Responsibility, Volume 35, Issue 3, Page 1536-1560, July 2026.
ABSTRACT A supportive ethical culture (EC) can encourage moral behavior among employees and help them avoid wrongdoing. One option for fostering EC is ethics training; its longer‐term effectiveness, however, has rarely been examined, especially in countries lacking strong regulatory environments.
Pablo Ruiz‐Palomino   +3 more
wiley   +1 more source

Outcomes of urgent gastrointestinal-related procedures in Latin America (LATAM-URG): a prospective multicentre study. [PDF]

open access: yesLancet Reg Health Am
Summary: Background: Urgent abdominal operations represent a large proportion of surgical care and are associated with substantial morbidity and mortality.
Latam Collaborative Colorectal Surgery Consortium   +1 more
europepmc   +2 more sources

Patient reported outcomes can improve performance status assessment: a pilot study

open access: yesJournal of Patient-Reported Outcomes, 2019
Background Patient performance status is routinely used in oncology to estimate physical functioning, an important factor in clinical treatment decisions and eligibility for clinical trials.
Joan E. Broderick   +14 more
doaj   +1 more source

Cytokine Levels and Human Herpesviruses in Saliva from Clinical Periodontal Healthy Subjects with Peri-Implantitis: A Case-Control Study

open access: yesMediators of Inflammation, 2018
This study evaluated the presence of cytokines (IL-1β, IL-2, IL-4, IL-6, MCP-1, MIP-1α, MIP-1β, and TNF-α) and human herpesvirus (HSV1, HSV2, EBV, CMV, VZV, HHV6, HHV7, and HHV8) in saliva samples taken from subjects with and without peri-implantitis ...
Jaime S. Marques Filho   +9 more
doaj   +1 more source

From Policy to Practice: Brazil's Pathway to Eliminating Vertical Transmission of HIV as a Public Health Milestone

open access: yesJournal of the International AIDS Society, Volume 29, Issue S1, June 2026.
ABSTRACT Introduction The elimination of vertical transmission of HIV is a global health priority endorsed by the Pan American Health Organization (PAHO) and the World Health Organization (WHO), aligned with the Sustainable Development Goals (SDGs). Brazil has made substantial progress towards this goal through sustained investment in universal health ...
Pâmela Cristina Gaspar   +58 more
wiley   +1 more source

A randomized, controlled phase II trial of neoadjuvant ado-trastuzumab emtansine, lapatinib, and nab-paclitaxel versus trastuzumab, pertuzumab, and paclitaxel in HER2-positive breast cancer (TEAL study)

open access: yesBreast Cancer Research, 2019
Background Neoadjuvant dual human epidermal growth factor receptor (HER2) blockade with trastuzumab and pertuzumab plus paclitaxel leads to an overall pathologic complete response (pCR) rate of 46%.
Tejal A. Patel   +16 more
doaj   +1 more source

Quality of life outcomes after robotic-assisted and video-assisted thoracoscopic surgery for early-stage non-small cell lung cancer. [PDF]

open access: yesJTCVS Open
Background: Limited research exists comparing the impacts of robotic-assisted thoracic surgery (RATS) and video-assisted thoracic surgery (VATS) on patients’ physical and mental health-related quality of life (QoL). Methods: A prospective cohort of stage
Zhang J   +7 more
europepmc   +2 more sources

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