Results 141 to 150 of about 103,512 (241)

Microscale Tattooing of Hydrogels and Cells: Benzoxaborole‐Driven Microcontact Printing (µCP) on Glycosylated Surfaces

open access: yesAngewandte Chemie International Edition, Accepted Article.
Microcontact printing (µCP) is a widely used technique for microscale surface patterning. In this study, we present a polymer‐supported µCP method for the patterning of (bioactive) glycosylated surfaces under hydrated conditions. Patterning is achieved by direct contact with a grooved polydimethylsiloxane (PDMS) stamp, whose surface was grafted with a ...
Nazim Pallab   +8 more
wiley   +1 more source

The Chemistry and Biology of the Tetrodotoxin Natural Product Family

open access: yesAngewandte Chemie International Edition, Accepted Article.
Tetrodotoxin is a neurotoxic marine alkaloid, first isolated in 1909 from pufferfish and named after the biological order tetraodontiformes. Since its structural elucidation in 1964, it has attracted the interest of synthetic organic chemists due to its exceptional polarity, complex architecture, and important biological activity.
Benedikt Nißl   +6 more
wiley   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

The Non-Coding RNA Journal Club: Highlights on Recent Papers-12. [PDF]

open access: yesNoncoding RNA, 2023
Shiu PKT   +26 more
europepmc   +1 more source

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